Evidence map›Paper›PMID 37801496›Full record

ArticleScience advances2023

Chromatin analysis of adult pluripotent stem cells reveals a unique stemness maintenance strategy.

Axel Poulet, Arcadia J Kratkiewicz, Danyan Li, Josien C van Wolfswinkel

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Signal control during tissue regeneration in adult animals.Nature reviews. Molecular cell biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Axel PouletDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-3415-8960
Arcadia J KratkiewiczDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.ORCID 0000-0003-4444-1863
Danyan LiDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-5894-4472
Josien C van WolfswinkelDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.ORCID 0000-0003-4221-3218
Yale University · USYale Cancer Center · US

Funding

Non-coding RNA In Stem Cell BiologyR35GM128619 · NIGMS · YALE UNIVERSITY · PI VAN WOLFSWINKEL, JOSEPHINA C · 2018 to 2022
$2.1M
Role of transposon regulation in the negligible senescence of S. mediterraneaR01AG078926 · NIA · YALE UNIVERSITY · PI Josephina C van Wolfswinkel · 2022 to 2026
$2.0M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
NIA NIH HHS R01 AG078926NIGMS NIH HHS R35 GM128619NIH HHS S10 OD030363
6 · The paper itself

Abstract

Many highly regenerative organisms maintain adult pluripotent stem cells throughout their life, but how the long-term maintenance of pluripotency is accomplished is unclear. To decipher the regulatory logic of adult pluripotent stem cells, we analyzed the chromatin organization of stem cell genes in the planarian

Indexed as

Adult Stem CellsPlanariansPluripotent Stem CellsAnimalsChromatinPromoter Regions, GeneticChromatin

Identifiers

PMID37801496
PMCPMC10558129
OpenAlexW4387397340

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.