Evidence map›Paper›PMID 37803009›Full record

ArticleNature communications2023

Improving model fairness in image-based computer-aided diagnosis.

Mingquan Lin, Tianhao Li, Yifan Yang, Gregory Holste, Ying Ding, Sarah H Van Tassel, Kyle Kovacs, George Shih, Zhangyang Wang, Zhiyong Lu and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Benchmarking Vision Encoders for Image Classification in Ophthalmology.Computational and structural biotechnology journal · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mingquan LinDepartment of Population Health Sciences, Weill Cornell Medicine, New York, USA. mil4012@med.cornell.edu.ORCID http://orcid.org/0000-0003-0862-6588
Tianhao LiSchool of Information, The University of Texas at Austin, Austin, TX, USA.
Yifan YangNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (NIH), Bethesda, MD, 20894, USA.ORCID http://orcid.org/0000-0003-4414-9176
Gregory HolsteDepartment of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0002-5657-3081
Ying DingSchool of Information, The University of Texas at Austin, Austin, TX, USA.
Sarah H Van TasselDepartment of Ophthalmology, Weill Cornell Medicine, New York, USA.
Kyle KovacsDepartment of Ophthalmology, Weill Cornell Medicine, New York, USA.
George ShihDepartment of Radiology, Weill Cornell Medicine, New York, USA.
Zhangyang WangDepartment of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.
Zhiyong LuNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (NIH), Bethesda, MD, 20894, USA.
Fei WangDepartment of Population Health Sciences, Weill Cornell Medicine, New York, USA.ORCID http://orcid.org/0000-0001-9459-9461
Yifan PengDepartment of Population Health Sciences, Weill Cornell Medicine, New York, USA. yip4002@med.cornell.edu.ORCID http://orcid.org/0000-0001-9309-8331

Funding

A framework to enhance radiology structured report by invoking NLP and DL: Models and ApplicationsR00LM013001 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI PENG, YIFAN · 2020 to 2022
$710k
Achieving Model Fairness on Automatic Primary Open-angle Glaucoma ScreeningR21EY035296 · NEI · WEILL MEDICAL COLL OF CORNELL UNIV · PI PENG, YIFAN · 2023 to 2023
$466k
NEI NIH HHS R21 EY035296NLM NIH HHS R00 LM013001
6 · The paper itself

Abstract

Deep learning has become a popular tool for computer-aided diagnosis using medical images, sometimes matching or exceeding the performance of clinicians. However, these models can also reflect and amplify human bias, potentially resulting inaccurate missed diagnoses. Despite this concern, the problem of improving model fairness in medical image classification by deep learning has yet to be fully studied. To address this issue, we propose an algorithm that leverages the marginal pairwise equal opportunity to reduce bias in medical image classification. Our evaluations across four tasks using four independent large-scale cohorts demonstrate that our proposed algorithm not only improves fairness in individual and intersectional subgroups but also maintains overall performance. Specifically, the relative change in pairwise fairness difference between our proposed model and the baseline model was reduced by over 35%, while the relative change in AUC value was typically within 1%. By reducing the bias generated by deep learning models, our proposed approach can potentially alleviate concerns about the fairness and reliability of image-based computer-aided diagnosis.

Indexed as

AlgorithmsDiagnosis, Computer-AssistedComputersHumansReproducibility of Results

Identifiers

PMID37803009
PMCPMC10558498

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.