Evidence map›Paper›PMID 37809094›Full record

ArticleFrontiers in immunology2023

Inflammation-mediated fibroblast activation and immune dysregulation in collagen VII-deficient skin.

Morgan Anderson-Crannage, Alex M Ascensión, Olga Ibanez-Solé, Hongwen Zhu, Edo Schaefer, Darcy Ottomanelli, Bruno Hochberg, Jian Pan, Wen Luo, Meijuan Tian and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Contribution of HMGB1 to keratinocyte inflammation in recessive dystrophic epidermolysis bullosa.JID innovations : skin science from molecules to population health · 2026
    Article
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  8. The Role of Fibroblasts in Dystrophic Epidermolysis Bullosa Pathogenesis and Current Treatment Approaches.JID innovations : skin science from molecules to population health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Morgan Anderson-CrannageDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Alex M AscensiónBiodonostia Health Research Institute, Tissue Engineering Group, San Sebastian, Spain.
Olga Ibanez-SoléBiodonostia Health Research Institute, Tissue Engineering Group, San Sebastian, Spain.
Hongwen ZhuDepartment of Research & Development, Guizhou Atlasus Technology Co., Ltd., Guiyang, China.
Edo SchaeferDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Darcy OttomanelliDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Bruno HochbergDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Jian PanDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Wen LuoDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Meijuan TianDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Yaya ChuDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Mitchell S CairoDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Ander IzetaBiodonostia Health Research Institute, Tissue Engineering Group, San Sebastian, Spain.
Yanling LiaoDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
New York Medical College · USBiogipuzkoa Health Research Institute · ESCentro de Estudios e Investigaciones Técnicas de Gipuzkoa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known about how it predisposes the tissue microenvironment preceding tumor formation. Recessive dystrophic epidermolysis bullosa (RDEB), a skin-blistering disease secondary to

Indexed as

Carcinoma, Squamous CellEpidermolysis Bullosa DystrophicaSkin NeoplasmsAnimalsCollagenCollagen Type VIICytokinesFibroblastsHumansInterleukin-1MiceTumor MicroenvironmentCOL7A1 protein, humanCollagenCollagen Type VIICytokinesInterleukin-1dermal microenvironmentepidermolysis bullosafibroblast activationimmune suppressioninflammationinterleukin-1single-cell RNA sequencingsquamous cell carcinoma

Identifiers

PMID37809094
PMCPMC10557493
OpenAlexW4386931959

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.