Evidence map›Paper›PMID 37812142›Full record

ArticleAJOB neuroscience

Disentangling Function from Benefit: Participant Perspectives from an Early Feasibility Trial for a Novel Visual Cortical Prosthesis.

Lilyana Levy, Hamasa Ebadi, Ally Peabody Smith, Lauren Taiclet, Nader Pouratian, Ashley Feinsinger

Open access · greenAbstract read
In one paragraph

Article in AJOB neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lilyana LevyDavid Geffen School of Medicine, University of California, Los Angeles.
Hamasa EbadiUniversity of Texas Southwestern Medical Center.
Ally Peabody SmithDavid Geffen School of Medicine, University of California, Los Angeles.
Lauren TaicletDavid Geffen School of Medicine, University of California, Los Angeles.
Nader PouratianUniversity of Texas Southwestern Medical Center.ORCID 0000-0002-0426-3241
Ashley FeinsingerDavid Geffen School of Medicine, University of California, Los Angeles.ORCID 0000-0002-0251-8810
University of California, Los Angeles · USSouthwestern Medical Center

Funding

Early Feasibility Clinical Trial of a Visual Cortical ProsthesisUH3NS103442 · NINDS · SECOND SIGHT MEDICAL PRODUCTS, INC. · PI GREENBERG, ROBERT JAY, PATEL, UDAY KIRIT · 2018 to 2023
$6.8M
NeuroEthics of Non-Therapeutic Invasive Human Neurophysiologic ResearchRF1MH121373 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI FEINSINGER, ASHLEY L, POURATIAN, NADER · 2020 to 2020
$1.3M
NIMH NIH HHS RF1 MH121373NINDS NIH HHS UH3 NS103442
6 · The paper itself

Abstract

Visual cortical prostheses (VCPs) have the potential to provide artificial vision for visually impaired persons. However, the nature and utility of this form of vision is not yet fully understood. Participants in the early feasibility trial for the Orion VCP were interviewed to gain insight into their experiences using artificial vision, their motivations for participation, as well as their expectations and assessments of risks and benefits. Analyzed using principles of grounded theory and an interpretive description approach, these interviews yielded six themes, including: the irreducibility of benefit to device functionality, mixed expectations for short-term device functionality and long-term technological advancement of visual prostheses, and a broad range of risks, concerns, and fears related to trial participation. We argue that these narratives motivate a nuanced set of ethical considerations related to the complex relationship between functionality and benefit, the intersection of user experience with disability justice, and the import of expectations and indirect risks on consent.

Indexed as

Feasibility StudiesVisual CortexVisual ProsthesisAdultAgedFemaleHumansMaleMiddle AgedCritical disability studiesemerging neurotechnologyneuroethicsparticipant perspectivesresearch ethicsvisual prostheses

Identifiers

PMID37812142
PMCPMC11001790
OpenAlexW4387441000

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.