Evidence map›Paper›PMID 37812939›Full record

ArticlePsychoneuroendocrinology2024

Threat exposure moderates associations between neural and physiological indices of emotion reactivity in adolescent females.

Meredith Gruhn, Adam Bryant Miller, Tory A Eisenlohr-Moul, Sophia Martin, Matthew G Clayton, Matteo Giletta, Paul D Hastings, Matthew K Nock, Karen D Rudolph, George M Slavich and 2 more

Open access · greenAbstract read
In one paragraph

Article in Psychoneuroendocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Research Review: Assessment of early-life adversity and trauma - cumulative risk and dimensional approaches.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Meredith GruhnUniversity of North Carolina at Chapel Hill, USA. Electronic address: meredith_gruhn@unc.edu.
Adam Bryant MillerUniversity of North Carolina at Chapel Hill, USA; RTI International, USA.
Tory A Eisenlohr-MoulUniversity of Illinois at Chicago, USA.
Sophia MartinUniversity of North Carolina at Chapel Hill, USA.
Matthew G ClaytonUniversity of North Carolina at Chapel Hill, USA.
Matteo GilettaDepartment of Developmental, Personality and Social Psychology, Ghent University, USA.
Paul D HastingsUniversity of California, Davis, USA.
Matthew K NockHarvard University, USA.
Karen D RudolphDepartment of Psychology, University of Illinois at Urbana-Champaign, USA.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA.
Mitchell J PrinsteinUniversity of North Carolina at Chapel Hill, USA.
Margaret A SheridanUniversity of North Carolina at Chapel Hill, USA.
University of North Carolina at Chapel Hill · USHarvard University Press · USUniversity of California, Davis · USUniversity of California, Los Angeles · USUniversity of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

Postdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5M
Multilevel Biomarkers for Suicidal Behavior: From Interpersonal Stress to Gene Expression in a Longitudinal Study of Adolescent GirlsR01MH107479 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NOCK, MATTHEW K, PRINSTEIN, MITCHELL J · 2015 to 2019
$4.6M
Adolescent Girls’ Risk for Suicide Across the Menstrual Cycle: Examining Stress and Negative Valence Systems LongitudinallyR01MH122446 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANDERSEN, ELIZABETH HELEN, EISENLOHR-MOUL, TORY ANNE · 2020 to 2025
$3.5M
Testing the predictive power of neural connectivity: Suicidal ideation in youth exposed to maltreatmentK01MH116325 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, ADAM BRYANT · 2018 to 2022
$898k
NICHD NIH HHS T32 HD040127NIMH NIH HHS K01 MH116325NIMH NIH HHS R01 MH107479NIMH NIH HHS R01 MH122446
6 · The paper itself

Abstract

Early life adversity (ELA) characterized by threat (e.g., abuse, witnessing violence) impacts neural and physiologic systems involved in emotion reactivity; however, research on how threat exposure impacts the interplay between these systems is limited. This study investigates ELA characterized by threat as a potential moderator of the association between (a) neural activity during a negative image processing fMRI task and (b) cortisol production following a modified Trier Social Stress Test (TSST). The sample is comprised of 117 young adolescent females (M

Indexed as

EmotionsHydrocortisoneAdolescentAmygdalaBrainChildFemaleFrontal LobeHumansMagnetic Resonance ImagingStress, PsychologicalHydrocortisoneAmygdalaCortisolEarly life adversityHippocampusNeuralThreat

Identifiers

PMID37812939
PMCPMC11034839
OpenAlexW4387035763

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.