ArticleTranslational pediatrics2023
Vascular function in a cohort of children, adolescents and young adults conceived through assisted reproductive technologies-results from the Munich heARTerY-study.
Article in Translational pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- Heterogeneous offspring growth in spontaneous versus in vitro fertilization pregnancies: a retrospective cohort study.Journal of assisted reproduction and genetics · 2026Article
- Innovations in assisted reproductive technologies: evaluating efficacy, safety, and long-term outcomes in female infertility.Obstetrics & gynecology science · 2026Review
- Age-Dependent Clinical Relevance of Lipoprotein(a): A Comprehensive Review from Childhood to Adulthood.Journal of clinical medicine · 2025Review
- Cardiorespiratory fitness and muscle strength in offspring conceived through assisted reproductive technologies: results from the Munich heARTerY-study.European journal of pediatrics · 2025Observational
- Twenty-Four Hour Ambulatory Blood Pressure Monitoring in Offspring Conceived Through Assisted Reproductive Technologies.Children (Basel, Switzerland) · 2025Article
- Influence of Dietary Intake on Carotid Maximum Intima-Media Thickness in Children Conceived Through Assisted Reproductive Techniques.Nutrients · 2025Observational
- Ultrasound evaluation of the cardiovascular system in offspring conceived through assisted reproductive technology.Journal of assisted reproduction and genetics · 2024Review
- Vascular Health of Females with History of Assisted Reproductive Technology.Journal of cardiovascular development and disease · 2024Article
- Cardiovascular health of offspring conceived by assisted reproduction technology: a comprehensive review.Frontiers in cardiovascular medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Over 8 million individuals worldwide have been conceived through assisted reproductive technologies (ART). There is conflicting evidence on the cardiovascular health of ART offspring. This study aimed to investigate vascular function in a cohort of children, adolescents and young adults conceived through ART compared to spontaneously conceived peers. Methods: Anthropometric variables, diet quality, level of physical activity and sedentary behavior were assessed. An extensive evaluation of vascular function was conducted. Blood pressure as well as endothelial function were evaluated. Carotid intima-media thickness was recorded sonographically. Blood draws were taken to determine blood lipids as well as HbA1c. Results: In total, 66 ART subjects conceived through in vitro fertilization (IVF) or intracytoplasmic sperm injection and 86 spontaneously conceived peers were included in this observational cohort study. Both groups were similar in age [11.31 (8.10-18.00) Conclusions: The results of the current study do not indicate a significantly lower vascular function in a cohort of children, adolescents and young adults conceived through ART compared to spontaneously conceived peers. Future studies should address the prevalence of elevated Lp(a) levels in infertile individuals who sought ART treatment. In addition, more studies evaluating body fat percentage as well as cardiovascular morbidity in adult ART subjects are required. For a more precise cardiovascular risk stratification, multi-center studies with larger ART sample sizes, preferably at adult age, are required in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.