Evidence map›Paper›PMID 37815182›Full record

ArticleCurrent drug delivery2024

Investigation of Antioxidant and Anti-inflammatory Properties of Berberine Nanomicelles:

Marjan Heidarzadeh, Mehriar Amininasab, Seyed Mahdi Rezayat, Seyyedeh Elaheh Mousavi

Abstract read
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In one paragraph

Article in Current drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marjan HeidarzadehDepartment of Cell and Molecular Biology, Kish International Campus, University of Tehran, Kish Island, Iran.
Mehriar AmininasabDepartment of Cell and Molecular Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran.
Seyed Mahdi RezayatDepartment of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Seyyedeh Elaheh MousaviDepartment of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRUniversity of Tehran · IR

Funding

Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS) 1400-1-209-49241
6 · The paper itself

Abstract

introductionIn the present study, neuroprotective effects of berberine (BBR) and berberine nanomicelle (BBR-NM) against lipopolysaccharides (LPS)-induced stress oxidative were investigated, and compared by evaluating their antioxidant and anti-inflammatory activities in PC12 cells, and rat brains. A fast, green, and simple synthesis method was used to prepare BBR-NMs.

methodThe prepared BBR-NMs were then characterized using dynamic light scattering (DLS), transmission electron microscopy (TEM), and scanning electron microscopy (SEM).

resultsMoreover,

conclusionOverall, BBR-NM demonstrated higher neuroprotective effects than free BBR, making it a promising treatment for improving many diseases caused by oxidative stress and inflammation.

Indexed as

Anti-Inflammatory AgentsAntioxidantsBerberineLipopolysaccharidesMicellesOxidative StressAnimalsBrainCell SurvivalMaleNanoparticlesNeuroprotective AgentsParticle SizePC12 CellsRatsReactive Oxygen SpeciesAnti-Inflammatory AgentsAntioxidantsBerberineLipopolysaccharidesMicellesNeuroprotective AgentsReactive Oxygen SpeciesBerberine nanomicelleCATcytokine.GPxROSSOD

Identifiers

PMID37815182
OpenAlexW4387473077

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.