Evidence map›Paper›PMID 37816536›Full record

Observational studyBMJ global health2023

Post COVID sequelae among COVID-19 survivors: insights from the Indian National Clinical Registry for COVID-19.

Gunjan Kumar, Ashish Bhalla, Aparna Mukherjee, Alka Turuk, Arunansu Talukdar, Subhasis Mukherjee, Pankaj Bhardwaj, Geetha R Menon, Damodar Sahu, Puspender Misra and 69 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

79 authors.

Gunjan Kumar *Clinical Studies & Trials Unit, Indian Council of Medical Research, New Delhi, India.
Ashish Bhalla *Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Aparna MukherjeeClinical Studies & Trials Unit, Indian Council of Medical Research, New Delhi, India aparna.sinha.deb@gmail.com.ORCID 0000-0001-7298-5097
Alka TurukClinical Studies & Trials Unit, Indian Council of Medical Research, New Delhi, India.
Arunansu TalukdarMedical College and Hospital Kolkata, Kolkata, India.
Subhasis MukherjeeCollege of Medicine and Sagore Dutta Hospital, Kolkata, India.
Pankaj BhardwajAll India Institute of Medical Sciences, Jodhpur, India.
Geetha R MenonNational Institute of Medical Statistics, New Delhi, India.
Damodar SahuNational Institute of Medical Statistics, New Delhi, India.
Puspender MisraNational Institute of Medical Statistics, New Delhi, India.
Lokesh Kumar SharmaIndian Council of Medical Research, New Delhi, India.
Ritin MohindraPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Samita SPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Vikas SuriPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Himadri DasMedical College and Hospital Kolkata, Kolkata, India.
Debasis SarkarMedical College and Hospital Kolkata, Kolkata, India.
Soumyadeep GhoshMedical College and Hospital Kolkata, Kolkata, India.
Priyanka GhoshCollege of Medicine and Sagore Dutta Hospital, Kolkata, India.
Moumita DuttaCollege of Medicine and Sagore Dutta Hospital, Kolkata, India.
Shreetama ChakrabortyCollege of Medicine and Sagore Dutta Hospital, Kolkata, India.
Deepak KumarAll India Institute of Medical Sciences, Jodhpur, India.
Manoj Kumar GuptaAll India Institute of Medical Sciences, Jodhpur, India.
Akhil Dhanesh GoelAll India Institute of Medical Sciences, Jodhpur, India.
Tridip Dutta BaruahAll India Institute of Medical Sciences, Raipur, India.
Pankaj Kumar KannaujeAll India Institute of Medical Sciences, Raipur, India.
Arvind Kumar ShuklaAll India Institute of Medical Sciences, Raipur, India.
Janakkumar R KhambholjaSmt NHL Municipal Medical College, Ahmedabad, India.
Amit PatelCIMS Hospital, Ahmedabad, India.
Nitesh ShahCIMS Hospital, Ahmedabad, India.
Sourin BhuniyaAll India Institute of Medical Sciences, Bhubaneswar, India.
Manoj Kumar PanigrahiAll India Institute of Medical Sciences, Bhubaneswar, India.
Prasanta Raghab MohapatraAll India Institute of Medical Sciences, Bhubaneswar, India.
Ashish PathakRD Gardi Medical College, Ujjain, India.
Ashish SharmaRD Gardi Medical College, Ujjain, India.
Mary JohnChristian Medical College and Hospital, Ludhiana, India.
Kiranpreet KaurChristian Medical College and Hospital, Ludhiana, India.
Vijay NongpiurNEIGRIHMS, Shillong, India.
Star PalaNEIGRIHMS, Shillong, India.
Sachin K ShivnitwarDr D Y Patil Medical College Hospital and Research Centre, Pune, India.
Bobba Rohil KrishnaDr D Y Patil Medical College Hospital and Research Centre, Pune, India.
Naveen DulhaniLate BRK Memorial Medical College, Jagdalpur, India.
Balkishan GuptaSP Medical College, Bikaner, India.
Jigyasa GuptaSP Medical College, Bikaner, India.
Sudhir BhandariSMS Medical College and Hospital, Jaipur, India.
Abhishek AgrawalSMS Medical College and Hospital, Jaipur, India.
H K AggarwalPandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, India.
Deepak JainPandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, India.
Arti D ShahSBKS Medical Institute and Research Centre, Vadodara, India.
Parshwa NaikSBKS Medical Institute and Research Centre, Vadodara, India.
Manisha PanchalGMERS Medical College, Himmatnagar, India.
Mayank AnderpaGMERS Medical College, Himmatnagar, India.
Nyanthung KikonDepartment of Health and Family Welfare, Government of Nagaland, Kohima, India.
Christina Nzani HumtsoeNaga Hospital Authority, Kohima, India.
Nikita SharmaMahatma Gandhi Medical College and Hospital, Jaipur, India.
Rajaat VohraMahatma Gandhi Medical College and Hospital, Jaipur, India.
Lipilekha PatnaikSOA IMS and SUM Hospital, Bhubaneswar, India.
Jagdish Prasad SahooSOA IMS and SUM Hospital, Bhubaneswar, India.
Rajnish JoshiAll India Institute of Medical Sciences, Bhopal, India.
Arun KokaneAll India Institute of Medical Sciences, Bhopal, India.
Yogiraj RayInstitute of Postgraduate Medical Education and Research, Kolkata, India.
Kruti RajvanshSmt NHL Municipal Medical College, Ahmedabad, India.
Hemang M PurohitSmt NHL Municipal Medical College, Ahmedabad, India.
Nehal M ShahSmt NHL Municipal Medical College, Ahmedabad, India.
Arun MadhariaESIC Gayatri Hospital, Chhattisgarh, India.
Simmi DubeGandhi Medical College, Bhopal, India.
Neha ShrivastavaGandhi Medical College, Bhopal, India.
Sushila KatariaMedanta, The Medicity, Gurgaon, India.
Mohammad ShameemJN Medical College, Aligarh, India.
Nazish FatimaJN Medical College, Aligarh, India.
Saumitra GhoshInstitute of Postgraduate Medical Education and Research, Kolkata, India.
Avijit HazraDepartment of Pharmacology, Institute of Postgraduate Medical Education and Research, Kolkata, India.
Himanshu DKing George Medical University, Lucknow, India.
Veeresh B SalgarGulbarga Institute of Medical Sciences, Gulbarga, India.
Santosh AlgurGulbarga Institute of Medical Sciences, Gulbarga, India.
Kala Yadhav M LShri Atal Bihari Vajpayee Medical College and Research Institution, Bengaluru, India.
Pavan Kumar MKakatiya Medical College, Warangal, India.
Samiran PandaIndian Council of Medical Research, New Delhi, India.ORCID 0000-0002-5077-6275
Mendu Vishnu Vardhana RaoNational Institute of Medical Statistics, New Delhi, India.
Balram BhargavaAll India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effects of COVID-19 infection persist beyond the active phase. Comprehensive description and analysis of the post COVID sequelae in various population groups are critical to minimise the long-term morbidity and mortality associated with COVID-19. This analysis was conducted with an objective to estimate the frequency of post COVID sequelae and subsequently, design a framework for holistic management of post COVID morbidities.

methodsFollow-up data collected as part of a registry-based observational study in 31 hospitals across India since September 2020-October 2022 were used for analysis. All consenting hospitalised patients with COVID-19 are telephonically followed up for up to 1 year post-discharge, using a prestructured form focused on symptom reporting.

resultsDyspnoea, fatigue and mental health issues were reported among 18.6%, 10.5% and 9.3% of the 8042 participants at first follow-up of 30-60 days post-discharge, respectively, which reduced to 11.9%, 6.6% and 9%, respectively, at 1-year follow-up in 2192 participants. Patients who died within 90 days post-discharge were significantly older (adjusted OR (aOR): 1.02, 95% CI: 1.01, 1.03), with at least one comorbidity (aOR: 1.76, 95% CI: 1.31, 2.35), and a higher proportion had required intensive care unit admission during the initial hospitalisation due to COVID-19 (aOR: 1.49, 95% CI: 1.08, 2.06) and were discharged at WHO ordinal scale 6-7 (aOR: 49.13 95% CI: 25.43, 94.92). Anti-SARS-CoV-2 vaccination (at least one dose) was protective against such post-discharge mortality (aOR: 0.19, 95% CI: 0.01, 0.03).

conclusionHospitalised patients with COVID-19 experience a variety of long-term sequelae after discharge from hospitals which persists although in reduced proportions until 12 months post-discharge. Developing a holistic management framework with engagement of care outreach workers as well as teleconsultation is a way forward in effective management of post COVID morbidities as well as reducing mortality.

Indexed as

COVID-19AftercareHumansPatient DischargeRegistriesSurvivorsCOVID-19descriptive studyepidemiologyhealth policy

Identifiers

PMID37816536
PMCPMC10565174

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.