Evidence map›Paper›PMID 37819980›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase.

Matthew G Alteen, Richard W Meek, Subramania Kolappan, Jil A Busmann, Jessica Cao, Zoe O'Gara, Ying Chou, Ratmir Derda, Gideon J Davies, David J Vocadlo

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  5. Universal Baseline forbioRxiv : the preprint server for biology · 2026
    Article
  6. A neutralizing APOA5 monoclonal antibody reduces amounts of lipoprotein lipase in capillaries and triggers hypertriglyceridemia.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  16. OGT and OGA: Sweet guardians of the genome.The Journal of biological chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Matthew G AlteenDepartment of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0002-9639-7668
Richard W MeekYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0002-1370-0896
Subramania KolappanDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0001-7469-2298
Jil A BusmannDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Jessica Cao48 Hour Discovery, Nanotechnology Research Centre, Edmonton, AB T6G 2M9, Canada.
Zoe O'Gara48 Hour Discovery, Nanotechnology Research Centre, Edmonton, AB T6G 2M9, Canada.
Ying Chou48 Hour Discovery, Nanotechnology Research Centre, Edmonton, AB T6G 2M9, Canada.
Ratmir Derda48 Hour Discovery, Nanotechnology Research Centre, Edmonton, AB T6G 2M9, Canada.
Gideon J DaviesYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0002-7343-776X
David J VocadloDepartment of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0001-6897-5558
Simon Fraser University · CAUniversity of Georgia · USUniversity of Alberta · CAUniversity of Southampton · GBUniversity of York · GB

Funding

CIHR PJT-156202
6 · The paper itself

Abstract

The modification of nucleocytoplasmic proteins by

Indexed as

BacteriophagesPeptidesAmino Acid SequenceHumansMutationN-AcetylglucosaminyltransferasesN-AcetylglucosaminyltransferasesO-GlcNAc transferasePeptidesallosteric inhibitionexositeglycosyltransferasephage displayX-ray structure

Identifiers

PMID37819980
PMCPMC10589721
OpenAlexW4387526415

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.