ArticleiScience2023
A network-based study reveals multimorbidity patterns in people with type 2 diabetes.
Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 15 citations in OpenAlex.
- Costs of Comorbidities and Complications Associated with Type 2 Diabetes: A Retrospective, Cohort Study.Advances in therapy · 2026Article
- Association of GLP-1RA discontinuation and risk of depressive and anxiety disorders in people with type 2 diabetes: a cohort study.Nature metabolism · 2026Article
- Co-occurrence network characteristics and key comorbidity node identification based on health examination indicators among rural older adults aged 65 and above.BMC geriatrics · 2026Article
- Life-course body size trajectories and the progression of cardio-renal-metabolic multimorbidity: a prospective UK biobank study.Nutrition & metabolism · 2026Article
- Observational
- Bridging Population Patterns and Individual Prediction: Framework for Prospective Multimorbidity Study.JMIR medical informatics · 2026Article
- Mapping sex-based multimorbidity networks in type 1 diabetes: a real-world study from Shanghai.Frontiers in endocrinology · 2026Article
- Network dynamics of metabolic disease continuum in older adults: a 7-year longitudinal cohort study in China.BMC geriatrics · 2025Article
- Impact of multimorbidity on healthcare costs in patients with type 2 diabetes in China: a longitudinal analysis of health insurance claims data.Archives of public health = Archives belges de sante publique · 2025Article
- Championing generalism in educational assessment: the MLA experience.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- Disease network analysis to reveal comorbidity patterns in hospitalized patients with COPD using large-scale administrative health data.Scientific reports · 2025Article
- Electronic Health Records: A Gateway to AI-Driven Multimorbidity Solutions-A Comprehensive Systematic Review.Journal of clinical medicine · 2025Review
- Multimorbidity patterns of mental disorders and physical diseases of adults in northeast China: a cross-sectional network analysis.Epidemiology and psychiatric sciences · 2025Article
- Article
- Influence of lifestyles on physical, psychological, and cognitive co-morbidity among older adults with diabetes in rural area.Frontiers in public health · 2025Article
- Multimorbidity in elderly patients with or without T2DM: A real-world cross-sectional analysis based on primary care and hospitalisation data.Journal of global health · 2024Article
- One path, two solutions: Network-based analysis identifies targetable pathways for the treatment of comorbid type II diabetes and neuropsychiatric disorders.Computational and structural biotechnology journal · 2024Article
- Gender disparities in physical, psychological, and cognitive multimorbidity among elderly hypertensive populations in rural regions.International journal for equity in health · 2024Article
- Impact of multimorbidity patterns on outcomes and treatment in patients with coronary artery disease.European heart journal open · 2024Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with type 2 diabetes mellitus (T2DM) are at a heightened risk of living with multiple comorbidities. However, the comprehension of the multimorbidity characteristics of T2DM is still scarce. This study aims to illuminate T2DM's prevalent comorbidities and their interrelationships using network analysis. Using electronic medical records (EMRs) from 496,408 Chinese patients with T2DM, we constructed male and female global multimorbidity networks and age- and sex-specific networks. Employing diverse network metrics, we assessed the structural properties of these networks. Furthermore, we identified hub, root, and burst diseases within these networks while scrutinizing their temporal trends. Our findings uncover interconnected T2DM comorbidities manifesting as emergence in clusters or age-specific outbreaks and core diseases in each sex that necessitate timely detection and intervention. This data-driven methodology offers a comprehensive comprehension of T2DM's multimorbidity, providing hypotheses for clinical considerations in the prevention and therapeutic strategies.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.