Evidence map›Paper›PMID 37822917›Full record

ReviewBioactive materials2024

Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging.

Min Jun Ko, Sunhong Min, Hyunsik Hong, Woojung Yoo, Jinmyoung Joo, Yu Shrike Zhang, Heemin Kang, Dong-Hyun Kim

Open access · goldAbstract readReview
In one paragraph

Review in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Two-step distance tuning of TMaterials today. Bio · 2026
    Article
  6. Iron-Based Nanoparticles as Delivery Tools.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Ferroptosis-induced immune modulation: a new frontier in glioblastoma therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  9. Review
  10. Stimuli-Responsive Supramolecular Biomaterials for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  11. FeCurrent cancer drug targets · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Min Jun KoDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Sunhong MinDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Hyunsik HongDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Woojung YooDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Jinmyoung JooDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Yu Shrike ZhangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital Harvard Medical School, Cambridge, MA, 02139, USA.
Heemin KangDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Dong-Hyun KimDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Korea University · KRNorthwestern University · USUlsan National Institute of Science and Technology · KRBrigham and Women's Hospital · US

Funding

Catheter-Directed Image-Guided Delivery of Cytostatic and Cytotoxic Combination Therapy to Liver TumorsR01CA218659 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2022
$1.9M
Image-Guided Transcatheter Delivery of Natural Killer Cell Therapy Augmented with IFN-Gamma Eluting MicrospheresR01EB026207 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2021
$1.4M
NCI NIH HHS R01 CA218659NIBIB NIH HHS R01 EB026207
6 · The paper itself

Abstract

Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to conventional cancer treatment regimens. Its effective use as a cancer therapy requires a precisely targeted approach, which can be facilitated by using nanoparticles and nanomedicine, and their use to enhance ferroptosis is indeed a growing area of research. While a few review papers have been published on iron-dependent mechanism and inducers of ferroptosis cancer therapy that partly covers ferroptosis nanoparticles, there is a need for a comprehensive review focusing on the design of magnetic nanoparticles that can typically supply iron ions to promote ferroptosis and simultaneously enable targeted ferroptosis cancer nanomedicine. Furthermore, magnetic nanoparticles can locally induce ferroptosis and combinational ferroptosis with diagnostic magnetic resonance imaging (MRI). The use of remotely controllable magnetic nanocarriers can offer highly effective localized image-guided ferroptosis cancer nanomedicine. Here, recent developments in magnetically manipulable nanocarriers for ferroptosis cancer nanomedicine with medical imaging are summarized. This review also highlights the advantages of current state-of-the-art image-guided ferroptosis cancer nanomedicine. Finally, image guided combinational ferroptosis cancer therapy with conventional apoptosis-based therapy that enables synergistic tumor therapy is discussed for clinical translations.

Indexed as

Diagnostic imagingFerroptosis cancer therapyMagnetic nanoparticlesMagnetic resonance imagingSynergistic cancer imaging and therapy

Identifiers

PMID37822917
PMCPMC10562133
OpenAlexW4387207069

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.