Evidence map›Paper›PMID 37823124›Full record

ArticleFood science & nutrition2023

The effects of unsaturated fatty acids on psoriasis: A two-sample Mendelian randomization study.

Hao Lei, Xin Chen, Baochen Cheng, Liumei Song, Ruiting Luo, Shengbang Wang, Tong Kang, Qian Wang, Yan Zheng

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hao LeiDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.ORCID https://orcid.org/0000-0003-1287-5499
Xin ChenState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology The Fourth Military Medical University Xi'an China.
Baochen ChengDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Liumei SongDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Ruiting LuoDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Shengbang WangDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Tong KangDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Qian WangTangdu Hospital, Air Force Military Medical University Xi'an China.
Yan ZhengDepartment of Dermatology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
First Affiliated Hospital of Xi'an Jiaotong University · CNAir Force Medical University · CNTang Du Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unsaturated fatty acids have been reported to be associated with the risk of psoriasis. However, the causal relationship between them remains unclear This study aimed to explore the causal relationship between unsaturated FAs and psoriasis. Firstly, we obtained genome-wide association study (GWAS) data for psoriasis from the FINNGEN database (number of cases = 4510, number of controls = 212,242) and different FA levels (number of samples = 114,999) from the IEU OpenGWAS Project. Secondly, the genetic correlation coefficient was calculated using linkage disequilibrium fractional regression. Thirdly, a two-sample Mendelian randomization (MR) analysis was performed using independent instrumental variables (

Indexed as

causalityMendelian randomizationpsoriasissingle nucleotide polymorphismsunsaturated fatty acids

Identifiers

PMID37823124
PMCPMC10563715
OpenAlexW4383263450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.