Evidence map›Paper›PMID 37823982›Full record

ArticleJournal of cancer survivorship : research and practice2025

Economic costs of family caregiving for persons with advanced stage cancer: a longitudinal cohort study.

Courtney Harold Van Houtven, Katherine E M Miller, Hailey J James, Ryan Blunt, Wenhan Zhang, Abigail Cadua Mariani, Sydney Rose, Gerard P Alolod, Maureen Wilson-Genderson, Valerie A Smith and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Exploring associations between area deprivation index, income, and loneliness among cancer caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Courtney Harold Van HoutvenDepartment of Population Health Sciences, Duke University, 215 Morris Street, Durham, NC, 27701, USA. courtney.vanhoutven@duke.edu.
Katherine E M MillerDepartment of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, USA.
Hailey J JamesRTI International, 3040 Cornwallis Road, Durham, NC, 27709, USA.
Ryan BluntDepartment of Social and Behavioral Sciences, Temple University, 1700 N. Broad Street, Philadelphia, PA, 19121, USA.
Wenhan ZhangDepartment of Population Health Sciences, Duke University, 215 Morris Street, Durham, NC, 27701, USA.
Abigail Cadua MarianiDepartment of Health Behavior and Policy, Virginia Commonwealth University, 830 E. Main Street, Richmond, VA, 23219, USA.
Sydney RoseDepartment of Social and Behavioral Sciences, Temple University, 1700 N. Broad Street, Philadelphia, PA, 19121, USA.
Gerard P AlolodDepartment of Social and Behavioral Sciences, Temple University, 1700 N. Broad Street, Philadelphia, PA, 19121, USA.
Maureen Wilson-GendersonDepartment of Social and Behavioral Sciences, Temple University, 1700 N. Broad Street, Philadelphia, PA, 19121, USA.
Valerie A SmithDepartment of Population Health Sciences, Duke University, 215 Morris Street, Durham, NC, 27701, USA.
Maria D ThomsonDepartment of Health Behavior and Policy, Virginia Commonwealth University, 830 E. Main Street, Richmond, VA, 23219, USA.
Laura A SiminoffDepartment of Social and Behavioral Sciences, Temple University, 1700 N. Broad Street, Philadelphia, PA, 19121, USA.

Funding

Informal caregiver burden in advanced cancer: Economic and health outcomesR01CA196576 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI SIMINOFF, LAURA A., THOMSON, MARIA D. · 2015 to 2019
$3.8M
NCI NIH HHS R01 CA196576NCI NIH HHS R01CA196576
6 · The paper itself

Abstract

purposeTo form a multifaceted picture of family caregiver economic costs in advanced cancer.

methodsA multi-site cohort study collected prospective longitudinal data from caregivers of patients with advanced solid tumor cancers. Caregiver survey and out-of-pocket (OOP) receipt data were collected biweekly in-person for up to 24 weeks. Economic cost measures attributed to caregiving were as follows: amount of OOP costs, debt accrual, perceived economic situation, and working for pay. Descriptive analysis illustrates economic outcomes over time. Generalized linear mixed effects models asses the association of objective burden and economic outcomes, controlling for subjective burden and other factors. Objective burden is number of activities and instrumental activities of daily living (ADL/IADL) tasks, all caregiving tasks, and amount of time spent caregiving over 24 h.

resultsOne hundred ninety-eight caregivers, 41% identifying as Black, were followed for a mean period of 16 weeks. Median 2-week out-of-pocket costs were $111. One-third of caregivers incurred debt to care for the patient and 24% reported being in an adverse economic situation. Whereas 49.5% reported working at study visit 1, 28.6% of caregivers at the last study visit reported working. In adjusted analysis, a higher number of caregiving tasks overall and ADL/IADL tasks specifically were associated with lower out-of-pocket expenses, a lower likelihood of working, and a higher likelihood of incurring debt and reporting an adverse economic situation.

conclusionsMost caregivers of cancer patients with advanced stage disease experienced direct and indirect economic costs. IMPLICATIONS FOR CANCER SURVIVORS: Results support the need to find solutions to lessen economic costs for caregivers of persons with advanced cancer.

Indexed as

CaregiversCost of IllnessHealth ExpendituresNeoplasmsActivities of Daily LivingAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesAdvanced cancerAdverse economic situationDebtEconomic costsEconomic strainFamily caregivingFinancial strainInformal careOut-of-pocket costsWork for pay

Identifiers

PMID37823982
PMCPMC13097396

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.