ArticlePloS one2023
Influence of femoral anteversion angle and neck-shaft angle on muscle forces and joint loading during walking.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of femoral derotation osteotomy on gait in ambulatory children with cerebral palsy: A systematic review and meta-analysis.Brazilian journal of physical therapyPooled it
- Femoral neck anteversion among five canid taxa.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Normative Values of Femoral Inclination Angle and Medial Proximal Femoral Angle: An MRI-Based Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Computational mechanobiological model combining epiphyseal, apophyseal, and appositional growth and inner bone remodeling of the juvenile femur.Biomedical engineering online · 2026Article
- Ontogenetic changes in femoral morphology and joint loads in children.Bone & joint research · 2026Article
- Femoral derotational osteotomies for version abnormalities: a mean ten-year follow-up.Bone & joint open · 2026Article
- Do we need medical imaging-informed musculoskeletal models for simulations in healthy adults? A new workflow based on magnetic resonance imaging highlights the importance of personalized geometry.PLoS computational biology · 2026Article
- Lower Extremity Torsional Deformity as an Overlooked Cause of Gait Dysfunction: A Case Report.JBJS case connector · 2026Article
- Reduced Muscle Strength Can Alter the Impact of Gait Modifications on Knee Cartilage Mechanics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Femoral bone growth predictions based on personalized multi-scale simulations: validation and sensitivity analysis of a mechanobiological model.Biomechanics and modeling in mechanobiology · 2025Article
- The Impact of Femoral Anteversion Correction on Clinical Outcomes in Total Hip Arthroplasty for Adult Developmental Dysplasia of the Hip.Journal of clinical medicine · 2025Article
- Muscle weakness but also contractures contribute to the progressive gait pathology in children with Duchenne muscular dystrophy: a simulation study.Journal of neuroengineering and rehabilitation · 2025Article
- Impact of Femoral and Tibial Torsion on Patellofemoral Loading in Individuals With Patellofemoral Instability.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- [Feasibility study on measuring anteversion angle of acetabular prosthesis after total hip arthroplasty using arbitrary point method].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Effects of femoral de-rotation on lower limb alignment using patient-specific guides with reliance on EOS scan, a retrospective study.Journal of orthopaedic surgery and research · 2025Article
- An Evaluation of Orthotics on In-Toeing or Out-Toeing Gait.Healthcare (Basel, Switzerland) · 2025Review
- Multiplanar Semicircular New-Generation Implant System Developed for Proximal Femur Periprosthetic Fractures: A Biomechanical Study.Medicina (Kaunas, Lithuania) · 2025Article
- Influence of hip morphology on gluteal muscle biomechanics: a computational modeling study.BMC musculoskeletal disorders · 2025Article
- Biomechanical analysis of hip, knee, and ankle joint contact forces during squats in elite powerlifters.PloS one · 2025Article
- To investigate the effect of neck-shaft angle in surgical hip dislocation combined with femoral neck rotational osteotomy in the treatment of osteonecrosis of the femoral head and to combine with finite element analysis.Frontiers in bioengineering and biotechnology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Femoral deformities, e.g. increased or decreased femoral anteversion (AVA) and neck-shaft angle (NSA), can lead to pathological gait patterns, altered joint loads, and degenerative joint diseases. The mechanism how femoral geometry influences muscle forces and joint load during walking is still not fully understood. The objective of our study was to investigate the influence of femoral AVA and NSA on muscle forces and joint loads during walking. We conducted a comprehensive musculoskeletal modelling study based on three-dimensional motion capture data of a healthy person with a typical gait pattern. We created 25 musculoskeletal models with a variety of NSA (93°-153°) and AVA (-12°-48°). For each model we calculated moment arms, muscle forces, muscle moments, co-contraction indices and joint loads using OpenSim. Multiple regression analyses were used to predict muscle activations, muscle moments, co-contraction indices, and joint contact forces based on the femoral geometry. We found a significant increase in co-contraction of hip and knee joint spanning muscles in models with increasing AVA and NSA, which led to a substantial increase in hip and knee joint contact forces. Decreased AVA and NSA had a minor impact on muscle and joint contact forces. Large AVA lead to increases in both knee and hip contact forces. Large NSA (153°) combined with large AVA (48°) led to increases in hip joint contact forces by five times body weight. Low NSA (108° and 93°) combined with large AVA (48°) led to two-fold increases in the second peak of the knee contact forces. Increased joint contact forces in models with increased AVA and NSA were linked to changes in hip muscle moment arms and compensatory increases in hip and knee muscle forces. Knowing the influence of femoral geometry on muscle forces and joint loads can help clinicians to improve treatment strategies in patients with femoral deformities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.