Evidence map›Paper›PMID 37824530›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The developmental hierarchy and scarcity of replicative slender trypanosomes in blood challenges their role in infection maintenance.

Stephen D Larcombe, Emma M Briggs, Nick Savill, Balazs Szoor, Keith R Matthews

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephen D LarcombeSchool of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0001-6173-046X
Emma M BriggsSchool of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0002-6740-8882
Nick SavillSchool of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0002-9769-6168
Balazs SzoorSchool of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0002-2805-9843
Keith R MatthewsSchool of Biological Sciences, Ashworth laboratories, Institute for Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0003-0309-9184
University of Edinburgh · GBWellcome Centre for Molecular Parasitology · GB

Funding

Wellcome Trust 206815Wellcome Trust 206815/Z/17/ZWellcome Trust 221717Wellcome Trust 221717/Z/20/Z
6 · The paper itself

Abstract

The development of

Indexed as

TrypanosomaTrypanosoma brucei bruceiAnimalsGene Expression ProfilingHumansMammalsMicePersistent Infectioncommitmentdifferentiationparasitesingle cellTrypanosoma brucei

Identifiers

PMID37824530
PMCPMC10589647
OpenAlexW4387581305

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.