Evidence mapPaperPMID 37824583Full record

SynthesisPloS one2023

The relationship between hemoglobin and

Kevin L Webb, Ellen K Gorman, Olaf H Morkeberg, Stephen A Klassen, Riley J Regimbal, Chad C Wiggins, Michael J Joyner, Shane M Hammer, Jonathon W Senefeld

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kevin L WebbDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Ellen K GormanDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Olaf H MorkebergDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0002-9236-8085
Stephen A KlassenDepartment of Kinesiology, Brock University, St. Catharines, Ontario, Canada.
Riley J RegimbalDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Chad C WigginsDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0002-6458-0142
Michael J Joyner *Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Shane M Hammer *Department of Kinesiology, Applied Health, and Recreation, Oklahoma State University, Stillwater, Oklahoma, United States of America.ORCID 0000-0003-1937-294X
Jonathon W Senefeld *Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0001-8116-3538
Mayo Clinic · USBrock University · CAOklahoma State University · US

Funding

Variant Hemoglobin and Cardiorespiratory Regulation in HumansR35HL139854 · NHLBI · MAYO CLINIC ROCHESTER · PI MICHAEL J JOYNER · 2021 to 2024
$3.3M
NHLBI NIH HHS F32 HL154320NHLBI NIH HHS R35 HL139854NHLBI NIH HHS T32 HL105355
6 · The paper itself

Abstract

objectiveThere is widespread agreement about the key role of hemoglobin for oxygen transport. Both observational and interventional studies have examined the relationship between hemoglobin levels and maximal oxygen uptake (

methodsA systematic search was performed on December 6th, 2021. The study procedures and reporting of findings followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Article selection and data abstraction were performed in duplicate by two independent reviewers. Primary outcomes were hemoglobin levels and

resultsData from 384 studies (226 observational studies and 158 interventional studies) were examined. For observational data, there was a positive association between absolute

conclusionThese findings suggest that

Indexed as

OxygenOxygen ConsumptionFemaleHumansMaleOxygen

Identifiers

PMID37824583
PMCPMC10569622
OpenAlexW4387568597

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.