Evidence map›Paper›PMID 37833251›Full record

ArticleCell death & disease2023

Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease.

Wenyan Hao, Hongxian Zhang, Peng Hong, Xin Zhang, Xuyang Zhao, Lulin Ma, Xiaoyan Qiu, Hao Ping, Dan Lu, Yuxin Yin

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Ferroptosis in kidney disease.Nature reviews. Nephrology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wenyan HaoInstitute of Systems Biomedicine, Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, 100191, PR China.
Hongxian ZhangDepartment of Urology, Peking University Third Hospital, Beijing, 100191, PR China.
Peng HongDepartment of Urology, Peking University Third Hospital, Beijing, 100191, PR China.
Xin ZhangInstitute of Systems Biomedicine, Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, 100191, PR China.
Xuyang ZhaoInstitute of Systems Biomedicine, Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, 100191, PR China.
Lulin MaDepartment of Urology, Peking University Third Hospital, Beijing, 100191, PR China.
Xiaoyan QiuDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing, 100191, PR China.
Hao PingDepartment of Urology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, PR China. pinghaotrh@ccmu.edu.cn.
Dan LuInstitute of Systems Biomedicine, Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, 100191, PR China. taotao@bjmu.edu.cn.ORCID 0000-0002-3000-5094
Yuxin YinInstitute of Systems Biomedicine, Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, 100191, PR China. yinyuxin@bjmu.edu.cn.ORCID 0000-0003-4102-0043
Peking University · CNBeijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephrolithiasis is highly prevalent and associated with the increased risk of kidney cancer. The tumor suppressor von Hippel-Lindau (VHL) is critical for renal cancer development, however, its role in kidney stone disease has not been fully elucidated until now. Here we reported VHL expression was upregulated in renal epithelial cells upon exposure to crystal. Utilizing Vhl

Indexed as

Carcinoma, Renal CellKidney NeoplasmsNephrolithiasisAnimalsKidneyMiceVon Hippel-Lindau Tumor Suppressor ProteinVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID37833251
PMCPMC10575931
OpenAlexW4387618081

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.