ArticleEuropean journal of clinical nutrition2024
Body composition of infants at 6 months of age using a 3-compartment model.
Article in European journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- An assessment of methods for measuring body composition in full-term infants: A systematic review.Pediatric research · 2026Pooled it
- Predicting total body water in infants aged 0.5-24 months and the implications for measuring breast milk intake: a secondary analysis of isotope dilution data.The American journal of clinical nutrition · 2025Article
- Paving the way for improved action: how nuclear techniques can advance the assessment of malnutrition.The American journal of clinical nutrition · 2025Article
- Should a single growth standard be used to judge the nutritional status of children under age 5 years globally: Yes.The American journal of clinical nutrition · 2024Article
- Should a single growth standard be used to judge the nutritional status of children under age 5 years globally? No.The American journal of clinical nutrition · 2024Article
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Authors and funding
9 authors at 9 institutions in 9 countries.
Funding
Abstract
BACKGROUND/
objectivesTwo compartment (2 C) models of body composition, including Air Displacement Plethysmography (ADP) and Deuterium Dilution (DD), assume constant composition of fat-free mass (FFM), while 3-compartment (3 C) model overcomes some of these assumptions; studies are limited in infants. The objective of the present study is to compare 3 C estimates of body composition in 6-mo. old infants from Australia, India, and South Africa, including FFM density and hydration, compare with published literature and to evaluate agreement of body composition estimates from ADP and DD.
methodsBody volume and water were measured in 176 healthy infants using ADP and DD. 3C-model estimates of fat mass (FM), FFM and its composition were calculated, compared between countries (age and sex adjusted) and with published literature. Agreement between estimates from ADP and DD were compared by Bland-Altman and correlation analyses.
resultsSouth African infants had significantly higher % FM (11.5%) and density of FFM compared to Australian infants. Australian infants had significantly higher % FFM (74.7 ± 4.4%) compared to South African infants (71.4 ± 5.0) and higher FFMI (12.7 ± 0.8 kg/m
conclusions3C-model estimates of body composition in infants differed between countries; future studies are needed to confirm these findings and investigate causes for the differences.
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Registered trials
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