Evidence map›Paper›PMID 37834980›Full record

ArticleJournal of clinical medicine2023

The Role of Adipose Tissue Mesenchymal Stem Cells in Colonic Anastomosis Healing in Inflammatory Bowel Disease: Experimental Study in Rats.

Georgios Ntampakis, Manousos-Georgios Pramateftakis, Orestis Ioannidis, Stefanos Bitsianis, Panagiotis Christidis, Savvas Symeonidis, Georgios Koliakos, Maria Karakota, Chrysanthi Bekiari, Anastasia Tsakona and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Georgios Ntampakis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-1681-487X
Manousos-Georgios Pramateftakis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Orestis Ioannidis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-0861-8783
Stefanos Bitsianis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Panagiotis Christidis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-4324-5051
Savvas Symeonidis4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Georgios KoliakosLaboratory of Biochemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-4350-9061
Maria KarakotaLaboratory of Biochemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Chrysanthi BekiariExperimental and Research Center, Papageorgiou General Hospital of Thessaloniki, 56403 Thessaloniki, Greece.
Anastasia TsakonaPathology Department, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Angeliki ChevaPathology Department, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Stamatios Aggelopoulos4th Department of General Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: A surgical operation on an inflamed bowel is, diachronically, a challenge for the surgeon, especially for patients with inflammatory bowel disease. Adipose tissue-derived mesenchymal stromal cells are already in use in clinical settings for their anti-inflammatory properties. The rationale of the current study was to use AdMSCs in high-risk anastomoses to monitor if they attenuate inflammation and prevent anastomotic leak. (2) Methods: a total of 4 groups of rats were subjected to a surgical transection of the large intestine and primary anastomosis. In two groups, DSS 5% was administered for 7 days prior to the procedure, to induce acute intestinal inflammation. After the anastomosis, 5 × 10

Indexed as

adipose tissue mesenchymal stromal cellsanastomotic leakbowel anastomosiscolorectal surgerydextran sodium sulfateinflammatory bowel disease

Identifiers

PMID37834980
PMCPMC10573964
OpenAlexW4387267823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.