ArticleDiagnostics (Basel, Switzerland)2023
Quadriceps Strength, Postural Stability, and Pain Mediation in Bilateral Knee Osteoarthritis: A Comparative Analysis with Healthy Controls.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06723587 (Chronic Effects of the Use of Instep Weights on Technical, Physical and Perceptual Parameters in Young Male Soccer Players), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Effects of the Use of Instep Weights on Technical, Physical and Perceptual Parameters in Young Male Soccer Players
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The efficacy and safety of pilates exercise in patients with knee osteoarthritis: a systematic review with meta-analysis of randomized controlled trials.Annals of medicine · 2025Pooled it
- Gait Analysis as a Measure of Physical Performance in Older Adults with Bilateral Knee Osteoarthritis.Medicina (Kaunas, Lithuania) · 2025Trial
- Association of thigh muscle status and longitudinal changes assessed by MRI with subsequent total hip arthroplasty: insights from the osteoarthritis initiative.Arthroplasty (London, England) · 2026Article
- The Effects of 24 Weeks Sensorimotor Training on Balance, Physical Function, and Pain in Women with Knee Osteoarthritis.Sports (Basel, Switzerland) · 2026Article
- Rehabilitation-oriented assessment of functional asymmetry and sensorimotor deficits following total knee arthroplasty: implications for therapeutic strategies in musculoskeletal care.Frontiers in medicine · 2026Article
- Sensorimotor dysfunction and altered pain sensitivity in early hip osteoarthritis: associations with hip proprioception and balance impairment.Frontiers in medicine · 2026Article
- Knee extensor strength normalised to body weight is associated with patient-reported outcomes at 12 months after open-wedge high tibial osteotomy.Journal of experimental orthopaedics · 2026Article
- Neuromotor frailty phenotype and fall risk in geriatrics with knee osteoarthritis: a cross-sectional analysis of physical therapy performance and psychometric outcomes.Frontiers in medicine · 2026Article
- Clinically feasible biomechanical assessment of lower limb strength and postural stability in adults aged 50-75 years with moderate knee osteoarthritis: implications for technology-enabled healthy aging.Frontiers in bioengineering and biotechnology · 2026Article
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- Correlation between quadriceps activation and proprioception in patients with knee osteoarthritis.Frontiers in bioengineering and biotechnology · 2025Article
- Reliability and reproducibility of the Kinvent K-push dynamometer for assessing quadriceps strength and force development in athletes and untrained individuals.Frontiers in physiology · 2025Article
- The Effects of Resistance Training on Pain, Strength, and Function in Osteoarthritis: Systematic Review and Meta-Analysis.Journal of personalized medicine · 2024Review
- Knee proprioception, muscle strength, and stability in Type 2 Diabetes Mellitus- A cross-sectional study.Heliyon · 2024Article
- Longitudinal weight and plantar pressure distribution while standing after tibial or malleolar fractures in patients with or without fracture union.Scientific reports · 2024Article
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- Article
- Balancing act: Unraveling the link between muscle strength, proprioception, and stability in unilateral hip osteoarthritis.PloS one · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Bilateral knee osteoarthritis (OA) poses significant challenges to individuals' functional abilities, including quadriceps strength, postural stability, and pain perception. Understanding the complex relationships among these factors is crucial for enhancing knee OA management strategies. The primary objective of this research is to evaluate and draw comparisons between the strength of the quadriceps and the level of postural stability in two distinct groups: individuals afflicted with bilateral knee OA and those who are healthy. Furthermore, the study seeks to examine the potential correlation between the strength of the quadriceps and the level of postural stability in individuals with knee OA. In addition to this, an investigation into the potential mediating effect of pain on the relationship between these physiological factors will also be conducted. A total of 95 participants with bilateral knee OA and 95 healthy controls were recruited. Quadriceps strength was assessed using dynamometry and postural stability was evaluated through anterior-posterior and medial-lateral sway measurements along with the ellipse area using a force plate. Pain levels were measured using the Visual Analog Scale (VAS). Mediation analysis was employed to explore the role of pain in mediating the relationship between quadriceps strength and postural stability. Statistical analyses included t-tests, Pearson correlation coefficients, and mediation analysis. Knee OA participants exhibited significantly lower quadriceps strength (1.08 Nm/kg ± 0.54) compared to controls (1.54 Nm/kg ± 0.57,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.