Evidence map›Paper›PMID 37836873›Full record

ArticleSensors (Basel, Switzerland)2023

Effect of Tryptic Digestion on Sensitivity and Specificity in MALDI-TOF-Based Molecular Diagnostics through Machine Learning.

Sumon Sarkar, Abigail Squire, Hanin Diab, Md Kaisar Rahman, Angela Perdomo, Babafela Awosile, Alexandra Calle, Jonathan Thompson

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sumon SarkarSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.ORCID 0000-0002-9008-1208
Abigail SquireSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.
Hanin DiabSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.
Md Kaisar RahmanSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.ORCID 0000-0001-7761-9846
Angela PerdomoSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.
Babafela AwosileSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.ORCID 0000-0002-4779-6515
Alexandra CalleSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.ORCID 0000-0003-3894-4181
Jonathan ThompsonSchool of Veterinary Medicine, Texas Tech University, 7671 Evans Dr., Amarillo, TX 79106, USA.ORCID 0000-0003-1550-2823
Texas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The digestion of protein into peptide fragments reduces the size and complexity of protein molecules. Peptide fragments can be analyzed with higher sensitivity (often > 10

Indexed as

Pathology, MolecularProteinsDigestionPeptide FragmentsPeptide HydrolasesSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationPeptide FragmentsPeptide HydrolasesProteinsartificial intelligence (AI)biomarkerdiagnosticmachine learningMALDI-TOFmolecular diagnosticsprecision medicineprotein digest

Identifiers

PMID37836873
PMCPMC10575185
OpenAlexW4386996187

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.