Evidence map›Paper›PMID 37843590›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Protective effects of Gα

Tobias Schröper, Dennis Mehrkens, Veronika Leiss, Frederik Tellkamp, Stefan Engelhardt, Stefan Herzig, Lutz Birnbaumer, Bernd Nürnberg, Jan Matthes

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Opposite effects of GαNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Tobias SchröperCenter of Pharmacology, Department II, University of Cologne and University Hospital Cologne, Cologne, Germany.
Dennis MehrkensDepartment of Internal Medicine III, University Hospital of Cologne, Cologne, Germany and Centre for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Veronika LeissDepartment of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomics, and Interfaculty Centre for Pharmacogenomics and Drug Research, Eberhard Karls Universität, Tübingen, Germany.
Frederik TellkampCECAD Research Centre Institute for Genetics, University of Cologne, Cologne, Germany.
Stefan EngelhardtInstitute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany.
Stefan HerzigCenter of Pharmacology, Department II, University of Cologne and University Hospital Cologne, Cologne, Germany.
Lutz BirnbaumerLaboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, USA.
Bernd NürnbergDepartment of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomics, and Interfaculty Centre for Pharmacogenomics and Drug Research, Eberhard Karls Universität, Tübingen, Germany.
Jan MatthesCenter of Pharmacology, Department II, University of Cologne and University Hospital Cologne, Cologne, Germany. jan.matthes@uni-koeln.de.
University of Cologne · DEUniversity of Tübingen · DEPontificia Universidad Católica Argentina · ARTechnical University of Munich · DETH Köln - University of Applied Sciences · DE

Funding

Transmembrane Signaling MechanismsZ01ES101643 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRNBAUMER, LUTZ · 2003 to 2008
$5.1M
Intramural NIH HHS Z01 ES101643
6 · The paper itself

Abstract

We have shown that in murine cardiomyopathy caused by overexpression of the β

Indexed as

CardiomyopathiesHeart FailureAnimalsGTP-Binding Protein alpha Subunits, Gi-GoMiceMice, Inbred C57BLMice, TransgenicMyocardiumProtein IsoformsProteomicsReceptors, Adrenergic, beta-1Adrb1 protein, mouseGnai3 protein, mouseGTP-Binding Protein alpha Subunits, Gi-GoProtein IsoformsReceptors, Adrenergic, beta-1Adrenergic receptorCardiomyopathyCardioprotectionGi proteinHeart failure

Identifiers

PMID37843590
PMCPMC10933181
OpenAlexW4387661953

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.