ArticleClinical & experimental optometry2024
Test-retest repeatability in macular retinal oximetry.
Article in Clinical & experimental optometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Evaluation of macular retinal oximetry across different levels of diabetic retinopathy: a cross sectional study.BMC ophthalmology · 2025Article
- Variations in Retinal Oxygen Saturation in a Diverse Healthy Population.Clinical optometry · 2024Article
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Authors and funding
3 authors.
Funding
Abstract
clinical relevanceEvaluation of retinal macular oxygen saturation in healthy controls can aid in understanding the pathological changes seen in similar locations of those with vascular diseases like diabetes.
backgroundThe aim of this study was to determine the test-retest repeatability of localised retinal oximetry measurements in the macula on the Zilia Oximeter within healthy subjects of different races, 18-40 years old. Oxygen saturation was measured between three time points within the same locations of the right eye.
methodsTwenty seven subjects were included (aged 26.3 ± 3.6 years). All were confirmed to have healthy retinas and at least 6/9 vision. Oximetry measurements were taken using the Zilia to acquire local oxygen saturation measurements (300 µm diameter) at four points 3.1 degrees from the fovea in the superior/temporal, superior/nasal, inferior/temporal, and inferior/nasal locations. Oximetry measurements were taken twice on the same day 20 minutes apart and then again 1-2 weeks later. Oximetry data was analysed with intraclass correlation between visits. To assess intrasubject repeatability, the Bland-Altman repeatability coefficient and coefficient of variation were calculated.
resultsAverage Intraclass correlation for the three acquisition times of the right eye was 0.78. The averaged intrasubject repeatability coefficient for the three acquisition times was 8.4. The averaged coefficient of variation was 5.4%.
conclusionThe Zilia oximeter has good macular test-retest repeatability; however, multiple measurements may be needed to ensure accuracy.
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