Evidence map›Paper›PMID 37844425›Full record

ArticleInternational journal of pediatric otorhinolaryngology2023

Association and risk factors of pediatric pulmonary hypertension with obstructive sleep apnea: A national study utilizing the Kids' Inpatient Database (KID).

Avraham Kohanzadeh, Benjamin Wajsberg, Elizabeth Yakubova, Meryl B Kravitz, Jaeun Choi, Qi Gao, Nicole J Sutton, Christina J Yang

Open access · greenAbstract read
In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Avraham KohanzadehAlbert Einstein College of Medicine, Bronx, NY, USA.
Benjamin WajsbergHead and Neck Institute, The Cleveland Clinic, Cleveland, OH, USA.
Elizabeth YakubovaDepartment of Anesthesiology, Mount Sinai Morningside and West Hospitals, New York, NY, USA.
Meryl B KravitzDepartment of Otorhinolaryngology - Head and Neck Surgery, Montefiore Medical Center, Bronx, NY, USA.
Jaeun ChoiAlbert Einstein College of Medicine, Department of Epidemiology and Population Health, Bronx, NY, USA.
Qi GaoAlbert Einstein College of Medicine, Department of Epidemiology and Population Health, Bronx, NY, USA.
Nicole J SuttonAlbert Einstein College of Medicine, Bronx, NY, USA; Department of Pediatrics, Division of Pediatric Cardiology, Children's Hospital at Montefiore, Bronx, NY, USA.
Christina J YangAlbert Einstein College of Medicine, Bronx, NY, USA; Department of Otorhinolaryngology - Head and Neck Surgery, Montefiore Medical Center, Bronx, NY, USA; Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY, USA. Electronic address: chyan@montefiore.org.
Albert Einstein College of Medicine · USCleveland Clinic · USMontefiore Medical Center · US

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
NCATS NIH HHS UL1 TR002556
6 · The paper itself

Abstract

STUDY

objectiveAssess the prevalence of and risk factors for pediatric pulmonary hypertension (PH) in the 2016 Kids' Inpatient Database (KID), including obstructive sleep apnea (OSA) and obesity.

methodsRetrospective cross-sectional cohort study utilizing 6,081,132 weighted pediatric discharges from the 2016 KID. Study variables included age, length of stay, mortality, gender, hospital region, primary payer, race, median household income for patient's ZIP code, OSA, central sleep apnea (CSA), obesity, Down syndrome, sickle cell disease (SCD), thalassemia, congenital heart disease (CHD), hypertension, asthma and chronic lung disease of prematurity (CLDP). PH was the primary outcome of interest. Bivariate and multivariable logistic regression models were utilized with odds ratios and 95 % confidence intervals.

resultsThe mean age was 3.76 years, the mean hospital length of stay was 3.85 days, 48.9 % were male, 52.6 % had government health insurance, 51.0 % were White, 16.1 % were Black, 21.1 % were Hispanic, 5.0 % were Asian or Pacific Islander, 0.80 % were Native American and 6.1 % identified as "other". The prevalence of PH was 0.21 % (12,777 patients). There were 37,631 patients with OSA and the prevalence of PH among this cohort was 3.3 %, over 10x greater than the overall prevalence of PH in the 2016 KID (0.21 %). Risk factors associated with PH included CLDP, CHD, Down syndrome, asthma, OSA, CSA, hypertension, SCD, obesity, race/ethnicity, government insurance, age, male gender (p < 0.0001), and hospital region (p = 0.0002).

conclusionsSeveral risk factors were independently associated with PH, such as OSA, CSA, obesity, asthma, and insurance status. Prospective multi-institutional studies are needed to assess the relationships between these risk factors, severity metrics, and causative links in the development of PH; in addition to identifying children with OSA who are most likely to benefit from cardiopulmonary screening prior to adenotonsillectomy. LEVEL OF EVIDENCE: Level III.

Indexed as

AsthmaDown SyndromeHeart Defects, CongenitalHypertensionHypertension, PulmonarySleep Apnea, CentralSleep Apnea, ObstructiveChildChild, PreschoolCross-Sectional StudiesFemaleHumansInpatientsMaleObesityProspective StudiesObstructive sleep apneaPediatricPulmonary hypertension

Identifiers

PMID37844425
PMCPMC10710769
OpenAlexW4387424270

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.