Evidence map›Paper›PMID 37845547›Full record

ReviewNature food2023

Stem cell-based strategies and challenges for production of cultivated meat.

T C Jara, K Park, P Vahmani, A L Van Eenennaam, L R Smith, A C Denicol

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature food, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Compression bioreactor for cultured meat.Current research in food science · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Scaling Cultured Meat: Challenges and Solutions for Affordable Mass Production.Comprehensive reviews in food science and food safety · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T C JaraDepartment of Animal Science, University of California Davis, Davis, CA, USA.ORCID 0000-0002-7711-1417
K ParkDepartment of Animal Science, University of California Davis, Davis, CA, USA.
P VahmaniDepartment of Animal Science, University of California Davis, Davis, CA, USA.ORCID 0000-0003-1537-1317
A L Van EenennaamDepartment of Animal Science, University of California Davis, Davis, CA, USA.ORCID 0000-0003-1562-162X
L R Smith *Department of Neurobiology, Physiology and Behavior, University of California Davis, Davis, CA, USA. lucsmith@ucdavis.edu.ORCID 0000-0002-7610-4231
A C Denicol *Department of Animal Science, University of California Davis, Davis, CA, USA.ORCID 0000-0003-2528-4874

Funding

National Science Foundation (NSF) 2021132
6 · The paper itself

Abstract

Cultivated meat scale-up and industrial production will require multiple stable cell lines from different species to recreate the organoleptic and nutritional properties of meat from livestock. In this Review, we explore the potential of stem cells to create the major cellular components of cultivated meat. By using developments in the fields of tissue engineering and biomedicine, we explore the advantages and disadvantages of strategies involving primary adult and pluripotent stem cells for generating cell sources that can be grown at scale. These myogenic, adipogenic or extracellular matrix-producing adult stem cells as well as embryonic or inducible pluripotent stem cells are discussed for their proliferative and differentiation capacity, necessary for cultivated meat. We examine the challenges for industrial scale-up, including differentiation and culture protocols, as well as genetic modification options for stem cell immortalization and controlled differentiation. Finally, we discuss stem cell-related safety and regulatory challenges for bringing cultivated meat to the marketplace.

Indexed as

Pluripotent Stem CellsCell DifferentiationCell LineMeatTissue Engineering

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.