Evidence map›Paper›PMID 37847724›Full record

ArticlePLoS computational biology2023

Integrated information theory (IIT) 4.0: Formulating the properties of phenomenal existence in physical terms.

Larissa Albantakis, Leonardo Barbosa, Graham Findlay, Matteo Grasso, Andrew M Haun, William Marshall, William G P Mayner, Alireza Zaeemzadeh, Melanie Boly, Bjørn E Juel and 6 more

Abstract read
In one paragraph

Article in PLoS computational biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed.

  1. Article
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  6. Review
  7. Article
  8. Article
  9. Article
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  12. Alpha Oscillations Track the Projection of Reactivated Memories into Conscious Awareness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Reflections on Consciousness in Intensive Care.Acta paediatrica (Oslo, Norway : 1992) · 2026
    Review
  19. Article
  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Larissa AlbantakisDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0003-1000-9917
Leonardo BarbosaDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Graham FindlayDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Matteo GrassoDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0002-2124-7147
Andrew M HaunDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
William MarshallDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0002-4779-6734
William G P MaynerDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Alireza ZaeemzadehDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Melanie BolyDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Bjørn E JuelDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Shuntaro SasaiDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Keiko FujiiDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Isaac DavidDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Jeremiah HendrenDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.
Jonathan P LangDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0001-8071-1344
Giulio TononiDepartment of Psychiatry, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0002-3892-4087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper presents Integrated Information Theory (IIT) 4.0. IIT aims to account for the properties of experience in physical (operational) terms. It identifies the essential properties of experience (axioms), infers the necessary and sufficient properties that its substrate must satisfy (postulates), and expresses them in mathematical terms. In principle, the postulates can be applied to any system of units in a state to determine whether it is conscious, to what degree, and in what way. IIT offers a parsimonious explanation of empirical evidence, makes testable predictions concerning both the presence and the quality of experience, and permits inferences and extrapolations. IIT 4.0 incorporates several developments of the past ten years, including a more accurate formulation of the axioms as postulates and mathematical expressions, the introduction of a unique measure of intrinsic information that is consistent with the postulates, and an explicit assessment of causal relations. By fully unfolding a system's irreducible cause-effect power, the distinctions and relations specified by a substrate can account for the quality of experience.

Indexed as

BrainInformation TheoryConsciousnessModels, Neurological

Identifiers

PMID37847724
PMCPMC10581496

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.