Evidence map›Paper›PMID 37847744›Full record

ArticleeLife2023

Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in

Berra Erkosar, Cindy Dupuis, Fanny Cavigliasso, Loriane Savary, Laurent Kremmer, Hector Gallart-Ayala, Julijana Ivanisevic, Tadeusz J Kawecki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Berra Erkosar *Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-1152-6772
Cindy Dupuis *Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
Fanny CavigliassoDepartment of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-7764-4934
Loriane SavaryDepartment of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
Laurent KremmerDepartment of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
Hector Gallart-AyalaMetabolomics Unit, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-2333-0646
Julijana IvanisevicMetabolomics Unit, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-8267-2705
Tadeusz J KaweckiDepartment of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-9244-1991
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile undernutrition has lasting effects on adult metabolism of the affected individuals, but it is unclear how adult physiology is shaped over evolutionary time by natural selection driven by juvenile undernutrition. We combined RNAseq, targeted metabolomics, and genomics to study the consequences of evolution under juvenile undernutrition for metabolism of reproductively active adult females of

Indexed as

MalnutritionStarvationAdaptation, PhysiologicalAnimalsDrosophilaDrosophila melanogasterFemaleHumansLarvaReproductionantagonistic pleiotropydietary restrictionD. melanogasterevolutionary biologyevolutionary constraintsexperimental evolutionmetabolomicsstarvation

Identifiers

PMID37847744
PMCPMC10637773
OpenAlexW4387707631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.