Evidence map›Paper›PMID 37850554›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2023

Time-restricted feeding regulates lipid metabolism under metabolic challenges.

Yiming Guo, Christopher Livelo, Girish C Melkani

Open access · greenAbstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. [Research progress on the effects of time-restricted eating on metabolic associated fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  6. Article
  7. Review
  8. Nutritional and Fasting Strategies for the Management of MASLD/MASH: An Integrative Review.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yiming GuoDepartment of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-4212-3784
Christopher LiveloDepartment of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-9944-8678
Girish C MelkaniDepartment of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-0353-4633
University of Alabama at Birmingham · US

Funding

Optimized Circadian Rhythms for the Prevention of Alzheimer's DiseaseRF1AG068550 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MELKANI, GIRISH C., PANDA, SATCHIDANANDA · 2020 to 2020
$3.0M
Molecular basis of circadian rhythms disruptions linked cardiometabolic disorders and their mitigation using dietary interventionR01AG065992 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MELKANI, GIRISH C. · 2019 to 2023
$1.9M
Optimized Circadian Rhythms for the Prevention of Alzheimer's DiseaseR01AG068550 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MELKANI, GIRISH C., PANDA, SATCHIDANANDA · 2024 to 2024
$736k
NIA NIH HHS R01 AG065992NIA NIH HHS R01 AG068550NIA NIH HHS RF1 AG068550NIH HHS AG065992NIH HHS AG068550
6 · The paper itself

Abstract

Dysregulation of lipid metabolism is a commonly observed feature associated with metabolic syndrome and leads to the development of negative health outcomes such as obesity, diabetes mellitus, non-alcoholic fatty liver disease, or atherosclerosis. Time-restricted feeding/eating (TRF/TRE), an emerging dietary intervention, has been shown to promote pleiotropic health benefits including the alteration of diurnal expression of genes associated with lipid metabolism, as well as levels of lipid species. Although TRF likely induces a response in multiple organs leading to the modulation of lipid metabolism, a majority of the studies related to TRF effects on lipids have focused only on individual tissues, and furthermore there is a lack of insight into potential underlying mechanisms. In this review, we summarize the current insights regarding TRF effects on lipid metabolism and the potential mechanisms in adipose tissue, liver, skeletal muscle, and heart, and conclude by outlining possible avenues for future exploration.

Indexed as

Lipid MetabolismObesityAdipose TissueCircadian RhythmEnergy MetabolismHumansLivercircadian rhythmlipid metabolismmetabolic challengesobesitytime-restricted feeding

Identifiers

PMID37850554
PMCPMC10841423
OpenAlexW4387728504

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.