Evidence map›Paper›PMID 37852972›Full record

ArticleNature communications2023

Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry.

Laura C Ristow, Andrew J Jezewski, Benjamin J Chadwick, Mark A Stamnes, Xiaorong Lin, Damian J Krysan

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  7. bioRxiv : the preprint server for biology · 2025
    Article
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  13. Article
  14. Acidic pH Reduces Fluconazole Susceptibility inJournal of microbiology and biotechnology · 2025
    Article
  15. Lack of an atypical PDR transporter generates an immunogenicbioRxiv : the preprint server for biology · 2025
    Article
  16. Article
  17. Article
  18. Discovery of CONature microbiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laura C RistowDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.ORCID http://orcid.org/0000-0002-3569-1492
Andrew J JezewskiDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.ORCID http://orcid.org/0000-0002-2004-1278
Benjamin J ChadwickDepartment of Plant Biology, University of Georgia, Athens, GA, 30602, USA.ORCID http://orcid.org/0000-0002-8244-6190
Mark A StamnesDepartment of Molecular Physiology and Biophysics, Caver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
Xiaorong LinDepartment of Plant Biology, University of Georgia, Athens, GA, 30602, USA.ORCID http://orcid.org/0000-0002-3390-8387
Damian J KrysanDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA. damian-krysan@uiowa.edu.
University of Iowa · USUniversity of Georgia · US

Funding

TRAINING IN MECHANISMS OF PARASITISMT32AI007511 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WEBER, MARY · 1996 to 2025
$8.1M
Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesisR01AI147541 · NIAID · UNIVERSITY OF IOWA · PI KRYSAN, DAMIAN J, LIN, XIAORONG · 2020 to 2025
$6.1M
NIAID NIH HHS R01 AI147541NIAID NIH HHS T32 AI007511
6 · The paper itself

Abstract

Cryptococcus spp. are environmental fungi that first must adapt to the host environment before they can cause life-threatening meningitis in immunocompromised patients. Host CO

Indexed as

CryptococcosisCryptococcus neoformansATP-Binding Cassette TransportersCarbon DioxideHumansPhosphatidylserinesPhospholipidsSaccharomyces cerevisiaeATP-Binding Cassette TransportersCarbon DioxidePhosphatidylserinesPhospholipids

Identifiers

PMID37852972
PMCPMC10584969
OpenAlexW4387734669

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.