Evidence map›Paper›PMID 37853273›Full record

ArticleCancer immunology, immunotherapy : CII2023

Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8

Xiangyu Hu, Shizhen Ding, Guotao Lu, Zhijie Lin, Liting Liao, Weiming Xiao, Yanbing Ding, Yu Zhang, Zhengbing Wang, Weijuan Gong and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Orchestration of Tumor-Associated Macrophages in the Tumor Cell-Macrophage-CD8International journal of biological sciences · 2025
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiangyu Hu *Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Shizhen Ding *Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Guotao LuDepartment of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Zhijie LinDepartment of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Liting LiaoDepartment of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Weiming XiaoDepartment of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Yanbing DingDepartment of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Yu ZhangSchool of Nursing, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Zhengbing WangDepartment of General Surgery, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Weijuan GongDepartment of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Xiaoqin JiaDepartment of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, 225001, People's Republic of China. xqjia@yzu.edu.cn.ORCID http://orcid.org/0000-0002-7143-5664
Yangzhou University · CNIntegrated Chinese Medicine (China) · CN

Funding

National Natural Science Foundation of China 81671547National Natural Science Foundation of China 81873866National Natural Science Foundation of China 81873867
6 · The paper itself

Abstract

Increased prevalence of cancer in obese individuals is involved with dyslipidemia- induced chronic inflammation and immune suppression. Although apolipoprotein C-III (ApoC3)-transgenic mice (ApoC3

Indexed as

InflammasomesNeoplasmsAnimalsApolipoprotein C-IIICD8-Positive T-LymphocytesMacrophagesMiceMice, Inbred C57BLPhospholipases A2, CytosolicToll-Like Receptor 2Apolipoprotein C-IIIInflammasomesPhospholipases A2, CytosolicToll-Like Receptor 2AntitumorApoC3CD8+ TInflammasomeMacrophage

Identifiers

PMID37853273
PMCPMC10992383
OpenAlexW4387764966

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.