Evidence map›Paper›PMID 37857597›Full record

ArticleNature communications2023

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo.

Rachel Sendor, Kristin Banek, Melchior M Kashamuka, Nono Mvuama, Joseph A Bala, Marthe Nkalani, Georges Kihuma, Joseph Atibu, Kyaw L Thwai, W Matthew Svec and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  13. Evidence of dengue virus transmission and a diversebioRxiv : the preprint server for biology · 2025
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  16. Seasonal variation and interspecies dynamics amongmedRxiv : the preprint server for health sciences · 2025
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  17. Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Rachel SendorDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. rachel.sendor@unc.edu.ORCID http://orcid.org/0000-0001-7259-1514
Kristin BanekInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-9219-2852
Melchior M KashamukaEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Nono MvuamaEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.ORCID http://orcid.org/0000-0003-2046-5836
Joseph A BalaEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Marthe NkalaniEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Georges KihumaEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Joseph AtibuEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Kyaw L ThwaiInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
W Matthew SvecUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Varun GoelDepartment of Geography, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Tommy NsekaEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jessica T LinInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jeffrey A BaileyDepartment of Pathology and Laboratory Medicine and Center for Computational Molecular Biology, Brown University, Providence, RI, USA.ORCID http://orcid.org/0000-0002-6899-8204
Michael EmchDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-2642-965X
Margaret CarrelDepartment of Geographical and Sustainability Sciences, University of Iowa, Iowa City, IA, USA.
Jonathan J JulianoDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Antoinette TshefuEcole de Santé Publique, Faculté de Médecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jonathan B ParrInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jonathan_parr@med.unc.edu.ORCID http://orcid.org/0000-0002-4465-9830
University of North Carolina at Chapel Hill · USUniversity of Kinshasa · CDBrown University · USUniversity of Iowa · US

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
Tracking the flow of malaria parasites and drug resistance within the DRC and across its bordersR01AI139520 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAILEY, JEFFREY A. · 2018 to 2023
$3.6M
RDT-undetectable Malaria in the DR Congo: Epidemiology and Development of AlternativesR01AI132547 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DINGLASAN, RHOEL DAVID RAMOS, JULIANO, JONATHAN J · 2018 to 2022
$3.6M
Epidemiological and Spatial Models of Malaria TransmissionR01AI107949 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MESHNICK, STEVEN RICHARD · 2014 to 2018
$2.5M
Mentoring in Translational Malaria GenomicsK24AI134990 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Jonathan J Juliano · 2018 to 2026
$1.6M
A longitudinal epidemiological and epidemiological study of malaria and its vectors in the Kinshasa provinceR01AI129812 · NIAID · KINSHASA SCHOOL OF PUBLIC HEALTH · PI TSHEFU, ANTOINETTE KITOTO · 2017 to 2021
$674k
Development of novel diagnostics for African non-falciparum malariaR21AI148579 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, JESSICA, PARR, JONATHAN BOYD · 2020 to 2021
$420k
Plasmodium ovale hypnozoite development and relapse: a coordinated in vivo in vitro studyR21AI152260 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAMS, JOHN H, LIN, JESSICA · 2021 to 2022
$418k
FIC NIH HHS D43 TW009340NIAID NIH HHS K24 AI134990NIAID NIH HHS L30 AI164494NIAID NIH HHS R01 AI107949NIAID NIH HHS R01 AI129812NIAID NIH HHS R01 AI132547NIAID NIH HHS R01 AI139520NIAID NIH HHS R21 AI148579NIAID NIH HHS R21 AI152260NIAID NIH HHS T32 AI070114Wellcome Trust
6 · The paper itself

Abstract

Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions. We estimated incidence and prevalence of PCR-confirmed non-falciparum and Plasmodium falciparum malaria infections within a longitudinal study conducted in Kinshasa, Democratic Republic of Congo (DRC) between 2015-2017. Children and adults were sampled at biannual household surveys and routine clinic visits. Among 9,089 samples from 1,565 participants, incidences of P. malariae, P. ovale spp., and P. falciparum infections by 1-year were 7.8% (95% CI: 6.4%-9.1%), 4.8% (95% CI: 3.7%-5.9%) and 57.5% (95% CI: 54.4%-60.5%), respectively. Non-falciparum prevalences were higher in school-age children, rural and peri-urban sites, and P. falciparum co-infections. P. falciparum remains the primary driver of malaria in the DRC, though non-falciparum species also pose an infection risk. As P. falciparum interventions gain traction in high-burden settings, continued surveillance and improved understanding of non-falciparum infections are warranted.

Indexed as

MalariaMalaria, FalciparumPlasmodium ovaleAdultChildDemocratic Republic of the CongoHumansLongitudinal StudiesPlasmodium falciparumPlasmodium malariaePrevalence

Identifiers

PMID37857597
PMCPMC10587068
OpenAlexW4387773175

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.