Evidence map›Paper›PMID 37859501›Full record

SynthesisEpidemiology and psychiatric sciences2023

COVID-19 risk, course and outcome in people with mental disorders: a systematic review and meta-analyses.

Patricio Molero, Gabriel Reina, Jan Dirk Blom, Miguel Ángel Martínez-González, Aischa Reinken, E Ronald de Kloet, Marc L Molendijk

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epidemiology and psychiatric sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
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  5. Observational
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  18. Article
  19. Long-Term Quality of Life after COVID-19 Infection: Cross-Sectional Study of Health Care Workers.International journal of environmental research and public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patricio MoleroDepartment of Psychiatry and Clinical Psychology, Clínica Universidad de Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0002-9287-9635
Gabriel ReinaNavarra Institute for Health Research (IdiSNA), Pamplona, Spain.ORCID https://orcid.org/0000-0003-4079-9753
Jan Dirk BlomInstitute of Psychology, Department of Clinical Psychology, Leiden University, Leiden, The Netherlands.
Miguel Ángel Martínez-GonzálezNavarra Institute for Health Research (IdiSNA), Pamplona, Spain.
Aischa ReinkenInstitute of Psychology, Department of Clinical Psychology, Leiden University, Leiden, The Netherlands.
E Ronald de KloetDivision of Endocrinology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Marc L MolendijkInstitute of Psychology, Department of Clinical Psychology, Leiden University, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-2819-0988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIt has been suggested that people with mental disorders have an elevated risk to acquire severe acute respiratory syndrome coronavirus 2 and to be disproportionally affected by coronavirus disease 19 (COVID-19) once infected. We aimed to analyse the COVID-19 infection rate, course and outcome, including mortality and long COVID, in people with anxiety, depressive, neurodevelopmental, schizophrenia spectrum and substance use disorders relative to control subjects without these disorders.

methodsThis study constitutes a preregistered systematic review and random-effects frequentist and Bayesian meta-analyses. Major databases were searched up until 27 June 2023.

resultsEighty-one original articles were included reporting 304 cross-sectional and prospective effect size estimates (median

conclusionsOnce infected, people with pre-existing mental disorders are at an elevated risk for a severe COVID-19 course and outcome, including long COVID and mortality, relative to people without pre-existing mental disorders, despite an infection risk not significantly increased.

Indexed as

COVID-19Mental DisordersBayes TheoremCross-Sectional StudiesHumansPost-Acute COVID-19 SyndromeProspective Studiescorona virus diseaseCOVID-19disease courseinfection risklong COVIDmental disorderssubstance use disorders

Identifiers

PMID37859501
PMCPMC10594644

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.