Evidence map›Paper›PMID 37859812›Full record

ArticleJournal of Cancer2023

Long Non-coding RNA Linc01224 Regulates Hypopharyngeal Squamous Cell Carcinoma Growth Through Interactions with miR-485-5p and IGF2BP3.

Lai Wei, Yuanhang Wu, Sisi Cai, Yulan Qin, Shuangchun Xing, Zhiqiang Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. [Research progress on the role and mechanism of IGF2BPs family in head and neck squamous carcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lai WeiDepartment of Otolaryngology, The Eighth Affiliated Hospital of Sun Yat-sen University, 518033, Shenzhen, China.
Yuanhang WuDepartment of Oncology, The First Affiliated Hospital of Dalian Medical University, 116000, Dalian, China.
Sisi CaiDepartment of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China.
Yulan QinDepartment of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, 116000, Dalian, China.
Shuangchun XingDepartment of Otolaryngology, The First Affiliated Hospital of Dalian Medical University, 116000, Dalian, China.
Zhiqiang WangDepartment of Otolaryngology, The Eighth Affiliated Hospital of Sun Yat-sen University, 518033, Shenzhen, China.
Affiliated Zhongshan Hospital of Dalian University · CNDalian Medical University · CNEighth Affiliated Hospital of Sun Yat-sen University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence illustrates that long non-coding RNAs (lncRNAs) play significant oncogenic roles, including hypopharyngeal squamous cell carcinoma (HSCC). The function and mechanism of long non-coding RNAs (lncRNAs) in hypopharyngeal squamous cell carcinoma (HSCC) have not been fully elucidated. Therefore, this study aimed to investigate the role of a specific lncRNA, linc01224, in regulating the miR-485-5p/IGF2BP3 axis in HSCC. We confirmed the lncRNA expression profiles in 5 pairs of HSCC and normal tissues by lncRNA sequencing. Another 28 HSCC tissues were further validated by quantitative real-time PCR (qRT-PCR). qRT-PCR was also used to detect the expression levels of linc01224, miR-485-5p and IGF2BP3 in HSCC cell lines. Next, functional experiments

Indexed as

Hypopharyngeal NeoplasmsIGF2BP3linc01224microRNAsmiR-485-5poncogenesRNA, Long Noncoding

Identifiers

PMID37859812
PMCPMC10583594
OpenAlexW4387194519

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.