Evidence map›Paper›PMID 37860759›Full record

ArticleiScience2023

AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected

Viviana Cobos Jiménez, Aviva Geretz, Andrey Tokarev, Philip K Ehrenberg, Selase Deletsu, Kawthar Machmach, Prakriti Mudvari, J Natalie Howard, Amanda Zelkoski, Dominic Paquin-Proulx and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Comprehensive Transcriptome Annotation of Thousands of HIV-1 Genomes.bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Viviana Cobos JiménezUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Aviva GeretzUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Andrey TokarevUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Philip K EhrenbergUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Selase DeletsuGeorge Washington University, Washington, DC, USA.
Kawthar MachmachUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Prakriti MudvariVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
J Natalie HowardGeorge Washington University, Washington, DC, USA.
Amanda ZelkoskiUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Dominic Paquin-ProulxUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Gregory Q Del PreteAIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Caroline SubraUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Eli A BoritzVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Alberto BosqueGeorge Washington University, Washington, DC, USA.
Rasmi ThomasUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Diane L BoltonUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Henry M. Jackson Foundation · USGeorge Washington University · USNational Institutes of Health · USWalter Reed Army Institute of Research · USFrederick National Laboratory for Cancer Research · US

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
NCI NIH HHS 75N91019D00024NCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003INIAID NIH HHS P30 AI117970
6 · The paper itself

Abstract

Persistent HIV-1 reservoirs of infected CD4 T cells are a major barrier to HIV-1 cure, although the mechanisms by which they are established and maintained

Indexed as

ImmunologyMicrobiologyMolecular biology

Identifiers

PMID37860759
PMCPMC10582365
OpenAlexW4386954611

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.