Evidence map›Paper›PMID 37867557›Full record

ReviewFrontiers in molecular biosciences2023

Cryo-electron microscopy in the fight against COVID-19-mechanism of virus entry.

Satish Bodakuntla, Christopher Cyrus Kuhn, Christian Biertümpfel, Naoko Mizuno

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in molecular biosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Electron Tomography as a Tool to Study SARS-CoV-2 Morphology.International journal of molecular sciences · 2024
    Review
  3. Factors affecting macromolecule orientations in thin films formed in cryo-EM.Acta crystallographica. Section D, Structural biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Satish Bodakuntla *Laboratory of Structural Cell Biology, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
Christopher Cyrus Kuhn *Laboratory of Structural Cell Biology, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
Christian BiertümpfelLaboratory of Structural Cell Biology, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
Naoko MizunoLaboratory of Structural Cell Biology, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
National Institutes of Health · USNational Heart Lung and Blood Institute · USNational Institute of Arthritis and Musculoskeletal and Skin Diseases · US

Funding

Molecular organization of pathways governing cell-shape formationZIAHL006264 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MIZUNO, NAOKO · 2021 to 2025
$11.6M
Molecular insights into the effects of SARS-Cov2 infection on the blood systemZIAHL006265 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MIZUNO, NAOKO · 2021 to 2023
$1.4M
Intramural NIH HHS ZIA HL006264Intramural NIH HHS ZIA HL006265
6 · The paper itself

Abstract

Cryogenic electron microscopy (cryo-EM) and electron tomography (cryo-ET) have become a critical tool for studying viral particles. Cryo-EM has enhanced our understanding of viral assembly and replication processes at a molecular resolution. Meanwhile,

Indexed as

ACE2COVID-19cryo-EMcryo-ETSARS-CoV-2spike protein

Identifiers

PMID37867557
PMCPMC10587472
OpenAlexW4387406514

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.