Evidence map›Paper›PMID 37869723›Full record

ReviewBioactive materials2024

Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications.

Jia Min Loh, Yun Jie Larissa Lim, Jin Ting Tay, Hui Mei Cheng, Hong Liang Tey, Kun Liang

Abstract readReview
In one paragraph

Review in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia Min LohA*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), Singapore.
Yun Jie Larissa LimA*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), Singapore.
Jin Ting TayA*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), Singapore.
Hui Mei ChengNational Skin Centre (NSC), Singapore.
Hong Liang TeyNational Skin Centre (NSC), Singapore.
Kun LiangA*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microneedles (MNs) is an emerging technology that employs needles ranging from 10 to 1000 μm in height, as a minimally invasive technique for various procedures such as therapeutics, disease monitoring and diagnostics. The commonly used method of fabrication, micromolding, has the advantage of scalability, however, micromolding is unable to achieve rapid customizability in dimensions, geometries and architectures, which are the pivotal factors determining the functionality and efficacy of the MNs. 3D printing offers a promising alternative by enabling MN fabrication with high dimensional accuracy required for precise applications, leading to improved performance. Furthermore, enabled by its customizability and one-step process, there is propitious potential for growth for 3D-printed MNs especially in the field of personalized and on-demand medical devices. This review provides an overview of considerations for the key parameters in designing MNs, an introduction on the various 3D-printing techniques for fabricating this new generation of MNs, as well as highlighting the advancements in biomedical applications facilitated by 3D-printed MNs. Lastly, we offer some insights into the future prospects of 3D-printed MNs, specifically its progress towards translation and entry into market.

Indexed as

3D printingBiosensingDrug deliveryExtraction of biological specimenMicroneedles

Identifiers

PMID37869723
PMCPMC10589728

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.