Evidence map›Paper›PMID 37870195›Full record

ArticleJournal of natural products2023

Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by

Drew V Carson, Yi Zhang, Larry So, Wai Ling Cheung-Lee, Alexis Jaramillo Cartagena, Seth A Darst, A James Link

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
    Review
  2. Article
  3. Antimicrobial peptides: from discovery to developmental applications.Applied and environmental microbiology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Drew V CarsonDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0002-4209-2199
Yi ZhangDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.
Larry SoDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-8863-7601
Wai Ling Cheung-LeeDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.
Alexis Jaramillo CartagenaLaboratory of Molecular Biophysics and Tri-Institutional Training Program in Chemical Biology, Rockefeller University, New York, New York 10065, United States.
Seth A DarstLaboratory of Molecular Biophysics and Tri-Institutional Training Program in Chemical Biology, Rockefeller University, New York, New York 10065, United States.
A James LinkDepartment of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-5066-9691
Princeton University · USRockefeller University · US

Funding

Structure, function, and regulation of the bacterial transcription cycleR35GM118130 · NIGMS · ROCKEFELLER UNIVERSITY · PI DARST, SETH A. · 2016 to 2025
$8.9M
Lasso Peptide DiscoveryR01GM107036 · NIGMS · PRINCETON UNIVERSITY · PI LINK, AARON JAMES · 2014 to 2022
$2.9M
NIGMS NIH HHS R01 GM107036NIGMS NIH HHS R35 GM118130
6 · The paper itself

Abstract

Through genome mining efforts, two lasso peptide biosynthetic gene clusters (BGCs) within two different species of

Indexed as

AchromobacterCystic FibrosisAntimicrobial PeptidesDNA-Directed RNA PolymerasesEscherichia coliHumansPeptidesAntimicrobial PeptidesDNA-Directed RNA PolymerasesPeptides

Identifiers

PMID37870195
PMCPMC10949989
OpenAlexW4387865233

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.