Evidence map›Paper›PMID 37870696›Full record

ReviewCurrent oncology reports2023

Novel Therapeutic Options for Small Cell Lung Cancer.

Stefania Canova, Benedetta Trevisan, Maria Ida Abbate, Francesca Colonese, Luca Sala, Alice Baggi, Sofia Paola Bianchi, Anna D'Agostino, Diego Luigi Cortinovis

Open access · hybridAbstract readReview
In one paragraph

Review in Current oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Adoptive cell therapies in thoracic malignancies: a comprehensive review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. [ORY-1001 inhibits glioblastoma cell growth by downregulating the Notch/HES1 pathwayNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Stefania Canova *SC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Benedetta Trevisan *SC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Maria Ida AbbateSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Francesca ColoneseSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Luca SalaSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Alice BaggiSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Sofia Paola BianchiRadiation Oncology Department, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Anna D'AgostinoSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Diego Luigi CortinovisSC Medical Oncology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy. diegoluigi.cortinovis@irccs-sangerardo.it.ORCID 0000-0001-7611-7369
Azienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe aim of this review is to focus on the recent advances in the molecular knowledge of small cell lung cancer (SCLC) and potential promising new treatment strategies, like targeting the DNA damage pathway, epigenetics, angiogenesis, and oncogenic drivers. RECENT

findingsIn the last few years, the addition of immunotherapy to chemotherapy has led to significant improvements in clinical outcomes in this complex neoplasia. Nevertheless, the prognosis remains dismal. Recently, numerous genomic alterations have been identified, and they may be useful to classify SCLC into different molecular subtypes (SCLC-A, SCLC-I, SCLC-Y, SCLC-P). SCLC accounts for 10-20% of all lung cancers, most patients have an extensive disease at the diagnosis, and it is characterized by poor prognosis. Despite the progresses in the knowledge of the disease, efficacious targeted treatments are still lacking. In the near future, the molecular characterisation of SCLC will be fundamental to find more effective treatment strategies.

Indexed as

Lung NeoplasmsSmall Cell Lung CarcinomaHumansImmunotherapyMolecular Targeted TherapyPrognosisImmunotherapyPARP inhibitorsSCLC classificationTarget therapy

Identifiers

PMID37870696
PMCPMC10640463
OpenAlexW4387865739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.