Evidence map›Paper›PMID 37873140›Full record

ArticlebioRxiv : the preprint server for biology2023

CED-5/CED-12 (DOCK/ELMO) can promote and inhibit F-actin formation via distinct motifs that target different GTPases.

Thejasvi Venkatachalam, Sushma Mannimala, Martha C Soto

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thejasvi VenkatachalamDepartment of Pathology and Laboratory Medicine, Rutgers - Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Sushma MannimalaDepartment of Pathology and Laboratory Medicine, Rutgers - Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Martha C SotoDepartment of Pathology and Laboratory Medicine, Rutgers - Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Rutgers, The State University of New Jersey · US

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular mechanisms initiating cell migrations in Caonorhabditis elegansR01GM081670 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2009 to 2023
$4.3M
Laser Spinning Disc Confocal System for live-cell and live-organism microscopyS10OD010572 · OD · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2012 to 2012
$386k
NIGMS NIH HHS P41 GM103311NIGMS NIH HHS R01 GM081670NIH HHS P40 OD010440NIH HHS S10 OD010572
6 · The paper itself

Abstract

Coordinated activation and inhibition of F-actin supports the movements of morphogenesis. Understanding the proteins that regulate F-actin is important, since these proteins are mis-regulated in diseases like cancer. Our studies of

Identifiers

PMID37873140
PMCPMC10592980
OpenAlexW4387366170

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.