Evidence map›Paper›PMID 37873938›Full record

ArticleEuropean stroke journal2024

Relationship of arterial stiffness and baseline vascular burden with new lacunes and microbleeds: A longitudinal cohort study.

Luis Mena, Juan José Mengual, Sonia María García-Sánchez, Carla Avellaneda-Gómez, Maria Àngels Font, Caterina Montull, Laura Castrillo, Pedro Blanch, Pere Castellanos, Mercè Lleixa and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European stroke journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Luis MenaNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Juan José MengualNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Sonia María García-SánchezNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Carla Avellaneda-GómezNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.ORCID 0000-0003-4851-1224
Maria Àngels FontNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Caterina MontullBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
Laura CastrilloBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
Pedro BlanchBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
Pere CastellanosInternal Medicine Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Mercè LleixaNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.
Montserrat Martín-BaraneraBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
Pedro ArmarioBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
Manuel Gómez-ChocoNeurology Department, Complex Hospitalari Universitari Moisès Broggi, Sant Joan Despí, Spain.ORCID 0000-0002-4191-7574
Bellvitge University Hospital · ESHospital de Sant Joan Despí Moisès Broggi · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArterial stiffness may have a significant impact on the development of cerebral small vessel disease (cSVD). PATIENTS AND

methodsWe obtained pulse wave velocity (24-h PWV) by means of ambulatory blood pressure monitoring (ABPM) in patients with a recent small subcortical infarct (RSSI). Patients with known cardiac or arterial embolic sources were excluded. Lacunes, microbleeds, white matter hyperintensities and enlarged perivascular spaces at baseline were assessed in a brain MRI and included in a cSVD score. A follow-up MRI was obtained 2 years later and assessed for the appearance of new lacunes or microbleeds. We constructed both unadjusted and adjusted models, and subsequently selected the optimal models based on the area under the curve (AUC) of the predicted probabilities.

resultsNinety-two patients (mean age 67.04 years, 69.6% men) were evaluated and 25 had new lacunes or microbleeds during follow-up. There was a strong correlation between 24-h PWV and age (

conclusionscSVD score is a stronger predictor for cSVD progression than age or hemodynamic parameters in patients with a RSSI.

Indexed as

Cerebral Small Vessel DiseasesHypercholesterolemiaVascular StiffnessAdultAgedBlood Pressure Monitoring, AmbulatoryCerebral HemorrhageCohort StudiesFemaleHumansLongitudinal StudiesMalePulse Wave AnalysisYoung AdultArterial stiffnesscerebral small vessel diseaselacunesmicrobleedspulse wave velocity

Identifiers

PMID37873938
PMCPMC10916807
OpenAlexW4387893420

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.