Evidence map›Paper›PMID 37881393›Full record

ReviewCureus2023

Cardiovascular Complications of Diabetes: From Microvascular to Macrovascular Pathways.

Mehreen Zakir, Neha Ahuja, Marvi Alais Surksha, Reya Sachdev, Yash Kalariya, Muhammad Nasir, Maham Kashif, Fnu Shahzeen, Arslan Tayyab, Muhammad Saood Moazzam Khan and 6 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 5 pooled it
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 5 syntheses or guidelines pooled it, 174 citations in OpenAlex.

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  19. Journal of biomedical research · 2026
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Mehreen ZakirMedicine, Sir Syed College of Medical Sciences, Karachi, PAK.
Neha AhujaGeneral Medicine, Chandka Medical College, Larkana, PAK.
Marvi Alais SurkshaMedicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Reya SachdevMedicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Yash KalariyaInternal Medicine, Civil Hospital Rajkot, Rajkot, IND.
Muhammad NasirMedicine, Rural Health Center (RHC) Dhonkal, Dhonkal, PAK.
Maham KashifMedicine, Khawaja Muhammad Safdar Medical College, Sialkot, PAK.
Fnu ShahzeenInternal Medicine, Jinnah Sindh Medical University, Karachi, PAK.
Arslan TayyabInternal Medicine, Quaid e Azam Medical College, Bahawalpur, PAK.
Muhammad Saood Moazzam KhanInternal Medicine, Quaid e Azam Medical College, Bahawalpur, PAK.
Mohsin JunejoMedicine, Chandka Medical College, Larkana, PAK.
Fnu Manoj KumarMedicine, Jinnah Sindh Medical University, Karachi, PAK.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.
Satesh KumarMedicine and Surgery, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, PAK.
Mahima KhatriMedicine and Surgery, Dow University of Health Sciences, Karachi, PAK.
Tamam MohamadCardiovascular Medicine, Wayne State University, Detroit, USA.
Jinnah Sindh Medical University · PKSree Gokulam Medical College and Research Foundation · INChandka Medical College · PKDow University of Health Sciences · PKFondazione Roma · ITShaheed Mohtarma Benazir Bhutto Medical University · PKSir Syed University of Engineering and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus, with a growing risk of developing complications, has a significant negative impact on cardiovascular health, including microvascular and macrovascular issues. This thorough narrative study methodically examines the complex connection between cardiovascular problems and diabetes. We start by thoroughly introducing diabetes mellitus, classifying its various forms, and discussing its growing global impact. Then, we examine retinopathy, nephropathy, and neuropathy in detail, illuminating their biology, clinical presentations, and treatment options. Moving on to macrovascular consequences, we investigate the complex relationships between diabetes and coronary artery disease, stroke, and peripheral arterial disease, emphasizing risk factors, diagnostic standards, and treatment plans designed for people with diabetes. The review analyzes the pathophysiological pathways that link diabetes to cardiovascular problems, including endothelial dysfunction, chronic inflammation, immune system dysregulation, and oxidative stress brought on by hyperglycemia. Additionally, we review the critical function of risk monitoring, assessment, and predictive tools in early detection. While highlighting current research paths and the need for tailored medical approaches to address this complex health issue, the story also includes prevention and management strategies, ranging from lifestyle changes to developing medications. This narrative review concludes by providing a thorough summary of current information, highlighting research gaps, and advocating for interdisciplinary efforts to reduce the cardiovascular effects of diabetes.

Indexed as

cardiovascularcvddiabetesmacrovascularmicrovascular

Identifiers

PMID37881393
PMCPMC10594042
OpenAlexW4386998464

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.