Evidence map›Paper›PMID 37886649›Full record

ArticleFrontiers in endocrinology2023

Serum uric acid is related to liver and kidney disease and 12-year mortality risk after myocardial infarction.

Luc Heerkens, Anniek C van Westing, Trudy Voortman, Isabella Kardys, Eric Boersma, Johanna M Geleijnse

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luc HeerkensDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands.
Anniek C van WestingDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands.
Trudy VoortmanDepartment of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Isabella KardysDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Eric BoersmaDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Johanna M GeleijnseDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands.
Erasmus MC · NLWageningen University & Research · NL

Funding

Alpha Omega TrialR01HL076200 · NHLBI · WAGENINGEN UNIVERSITY · PI KROMHOUT, DAAN · 2005 to 2008
$1.9M
NHLBI NIH HHS R01 HL076200
6 · The paper itself

Abstract

Objective: To study the associations of non-alcoholic fatty liver disease (NAFLD), chronic kidney disease (CKD), and serum uric acid (SUA) in patients with post-myocardial infarction (MI) patients, and the relationship of SUA with 12-year mortality risk. Methods: We included 3,396 patients (60-80 years old, 78% men) of the Alpha Omega Cohort. Multivariable prevalence ratios (PRs) were obtained for the association of NAFLD [fatty liver index (FLI), ≥77 (women) and ≥79 (men)] with CKD [estimated glomerular filtration rate (eGFR), <60 mL/min per 1.73 m Results: Median baseline FLI was 67 (men, 68; women, 64), and mean ± SD eGFR was 81 ± 20 mL/min per 1.73 m Conclusions: NAFLD and CKD were strongly associated, which was reflected by higher SUA concentrations. SUA was a strong predictor of 12-year mortality risk after MI.

Indexed as

Myocardial InfarctionNon-alcoholic Fatty Liver DiseaseRenal Insufficiency, ChronicAgedAged, 80 and overFemaleHumansMaleMiddle AgedUric AcidUric Acidglomerular filtration ratekidney diseasesmortalitynon-alcoholic fatty liver diseaseuric acid

Identifiers

PMID37886649
PMCPMC10599137
OpenAlexW4387537999

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.