Evidence map›Paper›PMID 37887299›Full record

ReviewCells2023

Epithelial Transport in Disease: An Overview of Pathophysiology and Treatment.

Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Laura Redondo-Flórez, Carlota Valeria Villanueva-Tobaldo, Rodrigo Yáñez-Sepúlveda, José Francisco Tornero-Aguilera

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Heat Stress in Japanese Quails (Animals : an open access journal from MDPI · 2024
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Vicente Javier Clemente-SuárezFaculty of Sports Sciences, Universidad Europea de Madrid, Tajo Street, s/n, 28670 Madrid, Spain.ORCID 0000-0002-2397-2801
Alexandra Martín-RodríguezFaculty of Sports Sciences, Universidad Europea de Madrid, Tajo Street, s/n, 28670 Madrid, Spain.ORCID 0000-0002-0087-4379
Laura Redondo-FlórezDepartment of Health Sciences, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, C/Tajo s/n, Villaviciosa de Odón, 28670 Madrid, Spain.ORCID 0000-0002-1006-7642
Carlota Valeria Villanueva-TobaldoDepartment of Health Sciences, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, C/Tajo s/n, Villaviciosa de Odón, 28670 Madrid, Spain.
Rodrigo Yáñez-SepúlvedaFaculty of Education and Social Sciences, Universidad Andres Bello, Viña del Mar 2520000, Chile.ORCID 0000-0002-9311-6576
José Francisco Tornero-AguileraFaculty of Sports Sciences, Universidad Europea de Madrid, Tajo Street, s/n, 28670 Madrid, Spain.ORCID 0000-0002-0747-8133
Universidad Europea de Madrid · ESUniversidad Andrés Bello · CLUniversity of the Coast · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial transport is a multifaceted process crucial for maintaining normal physiological functions in the human body. This comprehensive review delves into the pathophysiological mechanisms underlying epithelial transport and its significance in disease pathogenesis. Beginning with an introduction to epithelial transport, it covers various forms, including ion, water, and nutrient transfer, followed by an exploration of the processes governing ion transport and hormonal regulation. The review then addresses genetic disorders, like cystic fibrosis and Bartter syndrome, that affect epithelial transport. Furthermore, it investigates the involvement of epithelial transport in the pathophysiology of conditions such as diarrhea, hypertension, and edema. Finally, the review analyzes the impact of renal disease on epithelial transport and highlights the potential for future research to uncover novel therapeutic interventions for conditions like cystic fibrosis, hypertension, and renal failure.

Indexed as

Cystic FibrosisHypertensionCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsHumansIon TransportCystic Fibrosis Transmembrane Conductance Regulatorepithelial transportgenetic disordershormonal regulationion transportpathophysiologyrenal disease

Identifiers

PMID37887299
PMCPMC10605148
OpenAlexW4387653731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.