Evidence map›Paper›PMID 37887549›Full record

ReviewCurrent oncology (Toronto, Ont.)2023

A Review of the Clinical Features and Management of Systemic Congenital Mastocytosis through the Presentation of An Unusual Prenatal-Onset Case.

Valérie Larouche, Marie-Frédérique Paré, Pierre-Olivier Grenier, Anna Wieckowska, Eric Gagné, Rachel Laframboise, Nada Jabado, Isabelle De Bie

Open access · goldAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Valérie LaroucheDepartment of Pediatric Hemato-oncology, Centre Hospitalier Universitaire de Quebec-Université Laval, Quebec, QC G1V4G2, Canada.ORCID 0000-0002-9773-0995
Marie-Frédérique ParéMedecine Faculty, Laval University, Quebec, QC G1V4G2, Canada.
Pierre-Olivier GrenierDepartment of Dermatology, Centre Hospitalier Universitaire de Quebec-Université Laval, Quebec, QC G1V4G2, Canada.
Anna WieckowskaDepartement of Pediatric, Centre Hospitalier Universitaire de Quebec-Université Laval, Quebec, QC G1V4G2, Canada.
Eric GagnéDepartment of Pathology, Centre Hospitalier Universitaire de Quebec-Université Laval, Quebec, QC G1V4G2, Canada.
Rachel LaframboiseDepartment of Medical Genetics, Centre Hospitalier Universitaire de Quebec-Université Laval, Quebec, QC G1V4G2, Canada.
Nada JabadoDepartment of Pediatric Hemato-Oncology, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC G1V4G2, Canada.ORCID 0000-0003-2485-3692
Isabelle De BieDivision of Medical Genetics, Department of Specialized Medicine, McGill University Health Centre, Montreal, QC G1V4G2, Canada.ORCID 0000-0002-8721-2991
Centre hospitalier universitaire de Québec · CAMcGill University Health Centre · CAMontreal Children's Hospital · CAUniversité Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastocytosis is a heterogeneous group of rare hematological disorders that can occur in infancy. We report a 16-year-old girl who presented with an aggressive form of systemic congenital mastocytosis, associated with a significant global developmental delay, deafness, and multiple anomalies. At 4 years of age, she developed a germinoma presenting as an invasive spinal mass. Extensive cytogenetic, metabolic, and molecular genetic studies that included whole-exome sequencing studies revealed a

Indexed as

Congenital MicrotiaMastocytosisMastocytosis, CutaneousMastocytosis, SystemicAdolescentChildFemaleHumansProto-Oncogene Proteins c-kitProto-Oncogene Proteins c-kitCNS tumorcongenital mastocytosishearing lossKIT alterationmicrotiatyrosine kinase inhibitor

Identifiers

PMID37887549
PMCPMC10605361
OpenAlexW4387307488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.