Evidence map›Paper›PMID 37888618›Full record

ArticleToxins2023

Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage.

Se Yong Park, Ju-Hee Kang, Hyun Jin Jung, Jung Ho Hwang, Hyang Sook Chun, Yeo Sung Yoon, Seung Hyun Oh

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. The Benthic DinoflagellateMarine drugs · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Se Yong ParkDepartment of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
Ju-Hee KangCollege of Pharmacy, Gachon University, Incheon 21963, Republic of Korea.
Hyun Jin JungCollege of Pharmacy, Gachon University, Incheon 21963, Republic of Korea.
Jung Ho HwangCollege of Pharmacy, Gachon University, Incheon 21963, Republic of Korea.
Hyang Sook ChunFood Toxicology Laboratory, School of Food Science and Technology, Chung-Ang University, Anseong 17546, Republic of Korea.
Yeo Sung YoonDepartment of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
Seung Hyun OhCollege of Pharmacy, Gachon University, Incheon 21963, Republic of Korea.ORCID 0000-0003-3678-2772
Gachon University · KRSeoul National University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Okadaic acid (OA) and its analogues cause diarrhetic shellfish poisoning (DSP) in humans, and risk assessments of these toxins require toxicity equivalency factors (TEFs), which represent the relative toxicities of analogues. However, no human death by DSP toxin has been reported, and its current TEF value is based on acute lethality. To properly reflect the symptoms of DSP, such as diarrhea without death, the chronic toxicity of DSP toxins at sublethal doses should be considered. In this study, we obtained acute oral LD

Indexed as

Shellfish PoisoningAnimalsDiarrheaHumansLethal Dose 50MiceOkadaic AcidPyransdinophysistoxin 1Okadaic AcidPyransascitescomparative studydiarrheadiarrhetic shellfish poisoning

Identifiers

PMID37888618
PMCPMC10611360
OpenAlexW4386996323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.