Evidence map›Paper›PMID 37888619›Full record

ArticleToxins2023

Assessing Larval Zebrafish Survival and Gene Expression Following Sodium Butyrate Exposure and Subsequent Lethal Bacterial Lipopolysaccharide (LPS) Endotoxin Challenge.

Mary X Wang, Umesh K Shandilya, Xiang Wu, David Huyben, Niel A Karrow

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Endotoxins and Biological Implications-Review.Public health challenges · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mary X WangDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Umesh K ShandilyaDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0003-0148-8485
Xiang WuDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
David HuybenDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0001-7913-851X
Niel A KarrowDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As aquaculture production continues to grow, producers are looking for more sustainable methods to promote growth and increase fish health and survival. Butyrate is a short-chain fatty acid (SCFA) with considerable benefits to gut health, and in recent years, butyrate has been commonly used as an alternative to antimicrobials in livestock production. In this study, we aimed to assess the protective effects of sodium butyrate (NaB) on larval zebrafish subjected to a lethal

Indexed as

LipopolysaccharidesZebrafishAnimalsButyric AcidEndotoxinsGene ExpressionLarvaButyric AcidEndotoxinsLipopolysaccharidesDanio reriolipopolysaccharidePseudomonas aeruginosasodium butyrate

Identifiers

PMID37888619
PMCPMC10610854
OpenAlexW4386996326

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.