Serum and Synovial Levels of Cathepsin G and Cathepsin K in Patients with Psoriatic Arthritis and Their Correlation with Disease Activity Indices.

Stanislava Dimitrova Popova-Belova, Mariela Gencheva Geneva-Popova, Krasimir Iliev Kraev, Velichka Zaharieva Popova

Open access · goldAbstract read

In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

1.0field-weighted citation impact, top 22% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stanislava Dimitrova Popova-BelovaDepartment of Propedeutic of Internal Diseases, Faculty of Medicine, Medical University of Plovdiv, Clinic of Rheumatology, University General Hospital "Sveti Georgi", 4001 Plovdiv, Bulgaria.

Mariela Gencheva Geneva-PopovaDepartment of Propedeutic of Internal Diseases, Faculty of Medicine, Medical University of Plovdiv, Clinic of Rheumatology, University General Hospital "Sveti Georgi", 4001 Plovdiv, Bulgaria.

Krasimir Iliev KraevDepartment of Propedeutic of Internal Diseases, Faculty of Medicine, Medical University of Plovdiv, Clinic of Rheumatology, University General Hospital "Sveti Georgi", 4001 Plovdiv, Bulgaria.ORCID 0000-0002-1155-117X

Velichka Zaharieva PopovaDepartment of Propedeutic of Internal Diseases, Faculty of Medicine, Medical University of Plovdiv, University General Hospital "Kaspela", 4001 Plovdiv, Bulgaria.

University Multipurpose Hospital for Active Treatment "Sveti Georgi" · BGPlovdiv University · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective case-control study examined the relationship between the serum and synovial levels of cathepsin G (CatG) and cathepsin K (CatK) in patients with psoriatic arthritis (PsA) and their association with disease activity. Methods: This case-control study involved 156 PsA patients, 50 patients with gonarthrosis (GoA), and 30 healthy controls. The target parameters were measured using enzyme-linked immunosorbent assay (ELISA) kits. The serum levels of CatG and CatK were found to be significantly higher in PsA patients compared to both control groups (

Indexed as

cathepsin Gcathepsin Kpsoriatic arthritis

Identifiers

PMID37892071

DOI10.3390/diagnostics13203250

PMCPMC10606391

OpenAlexW4387775122

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.