Evidence map›Paper›PMID 37892456›Full record

ArticleNutrients2023

ECHOPvir: A Mixture of Echinacea and Hop Extracts Endowed with Cytoprotective, Immunomodulatory and Antiviral Properties.

Ester Percaccio, Marta De Angelis, Alessandra Acquaviva, Giovanna Nicotra, Claudio Ferrante, Gabriela Mazzanti, Silvia Di Giacomo, Lucia Nencioni, Antonella Di Sotto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ester PercaccioDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-3188-2259
Marta De AngelisLaboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Public Health and Infectious Diseases, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-1916-6508
Alessandra AcquavivaDepartment of Pharmacy, Botanic Garden "Giardino dei Semplici", Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-8776-1413
Giovanna NicotraEPO S.r.l., 20141 Milan, Italy.
Claudio FerranteDepartment of Pharmacy, Botanic Garden "Giardino dei Semplici", Università degli Studi "Gabriele d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0001-9431-9407
Gabriela MazzantiDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Silvia Di GiacomoDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0003-3049-6644
Lucia NencioniLaboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Public Health and Infectious Diseases, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0003-4427-4823
Antonella Di SottoDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-7467-1689

Funding

EPO S.r.l. EPO found (granted to G.M.)EU funding NextGeneration EU-MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases (Project n. PE00000007, INF-ACT, granted to L.N.)Italian Ministry of University and Research MUR PRIN 2020: B89J21033130001, granted to L.N.)Sapienza University of Rome Ateneo 2017 Grant (Prot. RM11715C82289AFE; granted to A.D.S.)Sapienza University of Rome Ateneo 2018 Grant (Prot. RP11816432CF7CF1, granted to L.N.)Sapienza University of Rome Ateneo 2021 (Prot. RP12117A62FD5A1A, granted to L.N.)Sapienza University of Rome SEED PNR 2021 (granted to A.D.S.)
6 · The paper itself

Abstract

Respiratory viral infections continue to pose significant challenges, particularly for more susceptible and immunocompromised individuals. Nutraceutical strategies have been proposed as promising strategies to mitigate their impact and improve public health. In the present study, we developed a mixture of two hydroalcoholic extracts from the aerial parts of

Indexed as

EchinaceaHumulusInfluenza A Virus, H1N1 SubtypeAnimalsAntioxidantsAntiviral AgentsHumansMiceNF-E2-Related Factor 2Plant ExtractsAntioxidantsAntiviral AgentsNF-E2-Related Factor 2Plant Extractsantioxidantechinaceaherbal extractshop coneshost defencesimmune systeminfluenza virusNrf2respiratory infectionsviruses

Identifiers

PMID37892456
PMCPMC10609862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.