Evidence map›Paper›PMID 37893017›Full record

ArticleBiomedicines2023

Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study.

Loredana Matiș, Bogdana Ariana Alexandru, Radu Fodor, Lucia Georgeta Daina, Timea Claudia Ghitea, Silviu Vlad

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Loredana MatișFaculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.
Bogdana Ariana AlexandruFaculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.
Radu FodorFaculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.
Lucia Georgeta DainaFaculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.
Timea Claudia GhiteaFaculty of Medicine and Pharmacy, Pharmacy Department, University of Oradea, 410068 Oradea, Romania.ORCID 0000-0001-8981-1958
Silviu VladFaculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania.
University of Oradea · RO

Funding

University of Oradea 410068
6 · The paper itself

Abstract

Probiotics, also known as psychobiotics, have been linked to cognitive functions, memory, learning, and behavior, in addition to their positive effects on the digestive tract. The purpose of this study is to examine the psychoemotional effects and cognitive functioning in children with gastrointestinal disorders who undergo psychobiotherapy. A total of 135 participants, aged 5-18 years, were divided into three groups based on the pediatrician's diagnosis: Group I (Control) consisted of 37 patients (27.4%), Group II included 65 patients (48.1%) with psychoanxiety disorders, and Group III comprised 33 individuals (24.4%) with psychiatric disorders. The study monitored neurotransmitter levels such as serotonin, GABA, glutamate, cortisol, and DHEA, as well as neuropsychiatric symptoms including headaches, fatigue, mood swings, hyperactivity, aggressiveness, sleep disorders, and lack of concentration in patients who had gastrointestinal issues such as constipation, diarrhea, and other gastrointestinal problems. The results indicate that psychobiotics have a significant impact on reducing hyperactivity and aggression, and improving concentration. While further extensive studies are needed, these findings offer promising insights into the complexity of a child's neuropsychic behavior and the potential for balancing certain behaviors through psychobiotics.

Indexed as

gastrointestinal disordersneuropsychological imbalanceneurotransmitterpsychobiotics

Identifiers

PMID37893017
PMCPMC10604742
OpenAlexW4387100461

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.