Evidence map›Paper›PMID 37893186›Full record

ReviewBiomedicines2023

Blood Coagulation and Thrombotic Disorders following SARS-CoV-2 Infection and COVID-19 Vaccination.

Metodija Sekulovski, Niya Mileva, Georgi Vasilev Vasilev, Dimitrina Miteva, Milena Gulinac, Monika Peshevska-Sekulovska, Lyubomir Chervenkov, Hristiana Batselova, Georgi Hristov Vasilev, Latchezar Tomov and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Metodija SekulovskiDepartment of Anesthesiology and Intensive Care, University Hospital Lozenetz, Kozyak Str., 1407 Sofia, Bulgaria.ORCID 0000-0001-8374-7756
Niya MilevaMedical Faculty, Medical University of Sofia, 1 Georgi Sofiiski Str., 1431 Sofia, Bulgaria.ORCID 0000-0002-4666-0181
Georgi Vasilev VasilevMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-3280-5060
Dimitrina MitevaMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-5931-2426
Milena GulinacMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.
Monika Peshevska-SekulovskaMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-8468-0132
Lyubomir ChervenkovDepartment of Diagnostic Imaging, Medical University of Plovdiv, Bul. Vasil Aprilov 15A, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-8380-5992
Hristiana BatselovaDepartment of Epidemiology and Disaster Medicine, Medical University of Plovdiv, University Hospital "St George", 4000 Plovdiv, Bulgaria.ORCID 0000-0002-6201-848X
Georgi Hristov VasilevMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-6314-6889
Latchezar TomovMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0003-1902-6473
Snezhina LazovaMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-5884-7760
Dobrin VassilevFaculty of Public Health and Healthcare, Ruse University Angel Kanchev, 7017 Ruse, Bulgaria.
Tsvetelina VelikovaMedical Faculty, Sofia University, St. Kliment Ohridski, Kozyak 1 Str., 1407 Sofia, Bulgaria.ORCID 0000-0002-0593-1272
Lozenetz Hospital · BGMedical University of Sofia · BGMedical University Plovdiv · BGSofia University "St. Kliment Ohridski" · BGUniversity Multipurpose Hospital for Active Treatment "Sveti Georgi" · BGAngel Kanchev University of Ruse · BGNew Bulgarian University · BGPlovdiv University · BG

Funding

European Union-NextGenerationEU, through the National Recovery and Resilience Plan of the Republic of Bulgaria BG-RRP-2.004-0008
6 · The paper itself

Abstract

Although abundant data confirm the efficacy and safety profile of the developed vaccines against COVID-19, there are still some concerns regarding vaccination in high-risk populations. This is especially valid for patients susceptible to thrombotic or bleeding events and hesitant people due to the fear of thrombotic incidents following vaccination. This narrative review focuses on various inherited and acquired thrombotic and coagulation disorders and the possible pathophysiologic mechanisms interacting with the coagulation system during immunization in view of the currently available safety data regarding COVID-19 vaccines. Inherited blood coagulation disorders and inherited thrombotic disorders in the light of COVID-19, as well as blood coagulation and thrombotic disorders and bleeding complications following COVID-19 vaccines, along with the possible pathogenesis hypotheses, therapeutic interventions, and imaging for diagnosing are discussed in detail. Lastly, the lack of causality between the bleeding and thrombotic events and COVID-19 vaccines is debated, but still emphasizes the importance of vaccination against COVID-19, outweighing the minimal risk of potential rare adverse events associated with coagulation.

Indexed as

blood coagulationblood disorderscerebral venous thrombosisCOVID-19COVID-19 vaccinesdisseminated intravascular coagulationhemophiliathrombocytopeniathrombophiliathrombotic eventsthrombotic incidents

Identifiers

PMID37893186
PMCPMC10604891
OpenAlexW4387723012

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.